The most commonly reported side effects of selpercatinib include malignant neoplasm progression, death, and diarrhoea, based on 1,185 FDA adverse event reports from 2020 to 2025. 2.8% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for selpercatinib.
These are voluntary reports and do not establish that selpercatinib caused these reactions.
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Other drugs that appear in adverse event reports alongside selpercatinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
48.9% of selpercatinib adverse event reports involve female patients and 39.2% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking selpercatinib when the adverse event was reported.
Showing 15 of 89 indications
Selpercatinib is sold under the brand name Retevmo.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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