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Secretin Side Effects

The most commonly reported side effects of secretin include chronic kidney disease, renal failure, and acute kidney injury, based on 75 FDA adverse event reports from 2008 to 2024. 6.7% of reports found the drug to be ineffective.

Secretin side effects

Percentages show how often each reaction appears relative to total reports for secretin.

1
Chronic Kidney Disease18.7%14
2
Renal Failure16.0%12
3
Acute Kidney Injury14.7%11
4
Dyspnoea12.0%9
5
End Stage Renal Disease12.0%9
6
Asthenia8.0%6
7
Fatigue8.0%6
8
Drug Ineffective6.7%5
9
Tubulointerstitial Nephritis6.7%5
10
Nephrogenic Anaemia6.7%5
11
Pancreatitis Acute5.3%4
12
Chest Pain5.3%4
13
Pyrexia5.3%4
14
Skin Exfoliation5.3%4
15
Psoriasis5.3%4

These are voluntary reports and do not establish that secretin caused these reactions.

Report severity

72.0%Serious54 reports
46.7%Hospitalizations35 reports
14.7%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Secretin drug interactions

Other drugs that appear in adverse event reports alongside secretin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Esomeprazole16.0%12
2
Omeprazole16.0%12
3
Methoxy-polyethylene-glycol-epoetin-beta14.7%11
4
Pantoprazole-sodium13.3%10
5
Lansoprazole6.7%5
6
Docetaxel4.0%3
7
Patiromer-sorbitex-calcium4.0%3
8
Ivacaftor2.7%2
9
Lumacaftor2.7%2
10
Abiraterone-acetate2.7%2
11
Degarelix-acetate2.7%2
12
Secukinumab2.7%2
13
Tipiracil2.7%2
14
Trifluridine2.7%2
15
Lenalidomide2.7%2

Taken alongside

1
Acetaminophen32.0%24
2
Ondansetron26.7%20
3
Lisinopril22.7%17
4
Insulin20.0%15
5
Aspirin18.7%14
6
Gabapentin18.7%14
7
Atorvastatin-calcium17.3%13
8
Albuterol17.3%13
9
Metoprolol17.3%13
10
Diphenhydramine16.0%12
11
Oxycodone16.0%12
12
Amlodipine16.0%12
13
Furosemide16.0%12
14
Ciprofloxacin14.7%11
15
Ergocalciferol14.7%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports secretin side effects

52.0% of secretin adverse event reports involve female patients and 42.7% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.0%
Male42.7%
Unknown5.3%

Age group

< 20.0%
2–110.0%
12–174.8%
18–6458.7%
65+36.5%

What is secretin used for

Conditions and purposes for which patients were taking secretin when the adverse event was reported.

Cardiovascular Event ProphylaxisChemotherapyComplication Associated With DeviceExocrine Pancreatic Function TestExocrine Pancreatic Function Test AbnormalHypothyroidismNuclear Magnetic Resonance ImagingPancreatic DisorderProduct Used For Unknown IndicationPersonal HygieneProduct Used For Unknown IndicationSecretin Test

Secretin brand names and reporting trend

Secretin is sold under brand names including Secreflo, Secretin-ferring.

Brand names

Secreflo66
Secretin-ferring15

Quarterly reports (20082024)

2008201620202024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking secretin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.