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Secnidazole Side Effects

The most commonly reported side effects of secnidazole include vomiting, nausea, and diarrhoea, based on 286 FDA adverse event reports from 2005 to 2025. 9.8% of reports found the drug to be ineffective.

Secnidazole side effects

Percentages show how often each reaction appears relative to total reports for secnidazole.

1
Vomiting27.3%78
2
Nausea17.8%51
3
Drug Ineffective9.8%28
4
Diarrhoea8.0%23
5
Wrong Technique In Product Usage Process7.7%22
6
Product Taste Abnormal7.3%21
7
Headache7.0%20
8
Dysgeusia6.3%18
9
Abdominal Pain5.6%16
10
No Adverse Event4.5%13
11
Malaise4.2%12
12
Chromaturia3.8%11
13
Foetal Exposure During Pregnancy3.5%10
14
Abdominal Discomfort3.5%10
15
Bacterial Vaginosis3.5%10

These are voluntary reports and do not establish that secnidazole caused these reactions.

Report severity

24.1%Serious69 reports
8.0%Hospitalizations23 reports
1.0%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Secnidazole drug interactions

Other drugs that appear in adverse event reports alongside secnidazole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tenofovir5.6%16
2
Lamivudine5.2%15
3
Efavirenz4.9%14
4
Metronidazole2.1%6
5
Sulfamethoxazole1.7%5
6
Penicillin1.7%5
7
Fluconazole1.4%4
8
Levomefolate-calcium1.0%3
9
Mycophenolate1.0%3
10
Estradiol1.0%3
11
Amoxicillin1.0%3
12
Tacrolimus1.0%3
13
Methotrexate0.7%2
14
Infliximab0.7%2
15
Ciprofloxacin0.7%2

Taken alongside

1
Ergocalciferol3.1%9
2
Metronidazole2.8%8
3
Fluconazole2.8%8
4
Levothyroxine-sodium2.8%8
5
Acetaminophen2.4%7
6
Folic-acid1.7%5
7
Ethinyl-estradiol1.7%5
8
Penicillin1.7%5
9
Nystatin1.4%4
10
Prednisone1.4%4
11
Ibuprofen1.4%4
12
Terbinafine1.4%4
13
Mebendazole1.4%4
14
Sulfamethoxazole1.4%4
15
Progesterone1.4%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports secnidazole side effects

81.5% of secnidazole adverse event reports involve female patients and 7.7% involve male patients. The largest age group is adult at 86%. These figures reflect who reports side effects, not underlying risk.

Sex

Female81.5%
Male7.7%
Unknown10.8%

Age group

< 23.9%
2–110.0%
12–172.6%
18–6485.5%
65+7.9%

What is secnidazole used for

Conditions and purposes for which patients were taking secnidazole when the adverse event was reported.

Abdominal PainAntibiotic ProphylaxisBacterial VaginosisBacterial VulvovaginitisBlastocystis InfectionBacterial InfectionBacterial VaginosisDiarrhoeaDrug Exposure During PregnancyDiarrhoeaFungal InfectionInflammationOvergrowth BacterialParasitic Infection ProphylaxisProduct Used For Unknown Indication

Showing 15 of 27 indications

Secnidazole brand names and reporting trend

Secnidazole is sold under the brand name Solosec.

Brand names

Solosec54

Quarterly reports (20052025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking secnidazole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.