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Scopolamine Side Effects

The most commonly reported side effects of scopolamine include off label use, nausea, and vomiting, based on 9,925 FDA adverse event reports from 2004 to 2025. 5.6% of reports found the drug to be ineffective.

Scopolamine side effects

Percentages show how often each reaction appears relative to total reports for scopolamine.

1
Off Label Use11.6%1,149
2
Nausea10.1%998
3
Vomiting7.5%743
4
Headache6.2%616
5
Diarrhoea5.9%588
6
Drug Ineffective5.6%560
7
Fatigue5.4%533
8
Dizziness5.2%521
9
Malaise4.3%422
10
Abdominal Pain4.0%397
11
Death3.8%373
12
Pain3.3%332
13
Pneumonia3.2%320
14
Constipation3.2%320
15
Dyspnoea3.2%315

These are voluntary reports and do not establish that scopolamine caused these reactions.

Report severity

77.1%Serious7,657 reports
37.9%Hospitalizations3,766 reports
12.7%Fatal1,259 reports

Seriousness is determined by the reporter, not by OpenClaim.

Scopolamine drug interactions

Other drugs that appear in adverse event reports alongside scopolamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Acetaminophen4.4%441
2
Clozapine4.0%396
3
Dexamethasone3.2%319
4
Tramadol-hydrochloride3.1%309
5
Duloxetine-hydrochloride3.1%306
6
Metoclopramide-hydrochloride3.0%296
7
Lansoprazole2.7%271
8
Prednisone2.7%268
9
Sertraline-hydrochloride2.7%265
10
Albuterol2.6%260
11
Hydromorphone-hydrochloride2.6%254
12
Topiramate2.4%243
13
Dihydrocodeine-bitartrate2.4%239
14
Venlafaxine2.3%229
15
Ciprofloxacin2.3%229

Taken alongside

1
Acetaminophen22.2%2,202
2
Ondansetron17.4%1,723
3
Omeprazole13.5%1,335
4
Albuterol11.5%1,143
5
Pantoprazole-sodium11.5%1,139
6
Lorazepam10.4%1,031
7
Levothyroxine-sodium8.9%881
8
Metoclopramide-hydrochloride8.9%879
9
Dexamethasone8.7%868
10
Furosemide8.5%843
11
Ergocalciferol8.5%841
12
Gabapentin8.4%832
13
Oxycodone7.9%781
14
Fluticasone7.3%725
15
Aspirin7.1%705

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports scopolamine side effects

57.8% of scopolamine adverse event reports involve female patients and 30.9% involve male patients. The largest age group is adult at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.8%
Male30.9%
Unknown11.3%

Age group

< 20.7%
2–112.8%
12–174.1%
18–6463.4%
65+29.0%

What is scopolamine used for

Conditions and purposes for which patients were taking scopolamine when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAbdominal RigidityAccidental ExposureAdverse EventAmyotrophic Lateral SclerosisAnaesthesiaAnalgesic TherapyAngina PectorisAntiemetic Supportive CareAnxietyAphrodisiac TherapyAppetite DisorderAptyalism

Showing 15 of 485 indications

Scopolamine brand names and reporting trend

Scopolamine is sold under the brand name Transderm Scop.

Brand names

Transderm Scop9,305

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking scopolamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.