The most commonly reported side effects of samidorphan include off label use, contraindicated product administered, and dizziness, based on 1,432 FDA adverse event reports from 2011 to 2025.
Percentages show how often each reaction appears relative to total reports for samidorphan.
These are voluntary reports and do not establish that samidorphan caused these reactions.
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Other drugs that appear in adverse event reports alongside samidorphan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
49.3% of samidorphan adverse event reports involve female patients and 34.0% involve male patients. The largest age group is adult at 88%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking samidorphan when the adverse event was reported.
Showing 15 of 69 indications
Samidorphan is sold under the brand name Lybalvi.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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