The most commonly reported side effects of safflower include off label use, general physical health deterioration, and condition aggravated, based on 184 FDA adverse event reports from 2004 to 2025.
Percentages show how often each reaction appears relative to total reports for safflower.
These are voluntary reports and do not establish that safflower caused these reactions.
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Other drugs that appear in adverse event reports alongside safflower. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
31.0% of safflower adverse event reports involve female patients and 63.0% involve male patients. The largest age group is elderly at 68%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking safflower when the adverse event was reported.
Showing 15 of 29 indications
Safflower is sold under the brand name Liposyn Ii 20%.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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