OpenClaim

Rocuronium Side Effects

The most commonly reported side effects of rocuronium include anaphylactic reaction, hypotension, and anaphylactic shock, based on 11,458 FDA adverse event reports from 2004 to 2025. 9.1% of reports found the drug to be ineffective.

Rocuronium side effects

Percentages show how often each reaction appears relative to total reports for rocuronium.

1
Anaphylactic Reaction9.9%1,133
2
Drug Ineffective9.1%1,047
3
Hypotension8.4%961
4
Anaphylactic Shock7.4%850
5
Cardiac Arrest4.7%541
6
Drug Interaction3.4%389
7
Off Label Use3.4%386
8
Bradycardia3.1%354
9
Tachycardia3.0%342
10
Bronchospasm2.5%290
11
Rash2.2%254
12
Urticaria2.2%250
13
Hypoxia2.1%238
14
Respiratory Failure2.0%230
15
Oxygen Saturation Decreased1.9%216

These are voluntary reports and do not establish that rocuronium caused these reactions.

Report severity

90.7%Serious10,388 reports
36.7%Hospitalizations4,203 reports
8.5%Fatal976 reports

Seriousness is determined by the reporter, not by OpenClaim.

Rocuronium drug interactions

Other drugs that appear in adverse event reports alongside rocuronium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Propofol29.0%3,318
2
Fentanyl18.9%2,171
3
Sevoflurane11.0%1,260
4
Remifentanil-hydrochloride10.0%1,149
5
Midazolam9.1%1,045
6
Sugammadex8.4%962
7
Lidocaine7.5%855
8
Dexamethasone6.8%779
9
Ketamine-hydrochloride6.6%757
10
Sufentanil-citrate6.1%700
11
Cefazolin-sodium5.1%581
12
Epinephrine4.5%521
13
Acetaminophen4.5%515
14
Ondansetron3.3%380
15
Apomorphine-hydrochloride3.3%374

Taken alongside

1
Propofol30.9%3,546
2
Fentanyl27.0%3,091
3
Midazolam17.1%1,955
4
Acetaminophen11.2%1,288
5
Lidocaine10.0%1,149
6
Remifentanil-hydrochloride9.1%1,037
7
Sevoflurane9.1%1,037
8
Dexamethasone8.9%1,015
9
Epinephrine8.4%963
10
Ondansetron7.5%860
11
Furosemide6.8%777
12
Cefazolin-sodium6.7%771
13
Heparin6.2%712
14
Insulin4.9%557
15
Sodium-chloride4.7%543

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports rocuronium side effects

44.6% of rocuronium adverse event reports involve female patients and 41.0% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.6%
Male41.0%
Unknown14.4%

Age group

< 24.8%
2–114.0%
12–173.7%
18–6459.1%
65+28.5%

What is rocuronium used for

Conditions and purposes for which patients were taking rocuronium when the adverse event was reported.

AbdominoplastyAcute Lymphocytic LeukaemiaAcute Respiratory Distress SyndromeAdenoidectomyAdenotonsillectomyAgitationAirway Patency Device InsertionAllergy TestAlloimmunisationAnaesthesiaAnaesthesia ProcedureAnaesthesia ReversalAnaesthetic PremedicationAnalgesic Intervention Supportive TherapyAnalgesic Therapy

Showing 15 of 423 indications

Rocuronium brand names and reporting trend

Rocuronium is sold under the brand name Zemuron.

Brand names

Zemuron12,591

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking rocuronium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.