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Rezafungin Side Effects

The most commonly reported side effects of rezafungin include off label use, no adverse event, and product prescribing issue, based on 122 FDA adverse event reports from 2022 to 2025.

Rezafungin side effects

Percentages show how often each reaction appears relative to total reports for rezafungin.

1
Off Label Use40.2%49
2
No Adverse Event9.8%12
3
Product Prescribing Issue9.8%12
4
Hypokalaemia4.9%6
5
Death4.9%6
6
Drug Resistance4.1%5
7
Thrombosis3.3%4
8
Aspergillus Infection3.3%4
9
Embolism3.3%4
10
Salivary Gland Enlargement3.3%4
11
Dizziness3.3%4
12
Pyrexia3.3%4
13
Nausea3.3%4
14
Product Use Issue3.3%4
15
Product Dose Omission Issue3.3%4

These are voluntary reports and do not establish that rezafungin caused these reactions.

Report severity

50.0%Serious61 reports
22.1%Hospitalizations27 reports
12.3%Fatal15 reports

Seriousness is determined by the reporter, not by OpenClaim.

Rezafungin drug interactions

Other drugs that appear in adverse event reports alongside rezafungin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Amphotericin-b8.2%10
2
Voriconazole4.9%6
3
Anidulafungin4.9%6
4
Fluconazole4.1%5
5
Posaconazole3.3%4
6
Apixaban3.3%4
7
Aspirin3.3%4
8
Anifrolumab-fnia1.6%2
9
Caspofungin-acetate1.6%2
10
Albuterol1.6%2
11
Cyclophosphamide0.8%1
12
Flucytosine0.8%1
13
Micafungin-sodium0.8%1
14
Duloxetine-hydrochloride0.8%1
15
Isavuconazonium-sulfate0.8%1

Taken alongside

1
Omeprazole7.4%9
2
Bisoprolol-fumarate4.9%6
3
Acetaminophen4.9%6
4
Dexamethasone4.1%5
5
Micafungin-sodium4.1%5
6
Prednisone4.1%5
7
Aspirin4.1%5
8
Mirtazapine4.1%5
9
Levofloxacin4.1%5
10
Vancomycin3.3%4
11
Amphotericin-b3.3%4
12
Cyanocobalamin3.3%4
13
Losartan-potassium3.3%4
14
Linagliptin3.3%4
15
Posaconazole3.3%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports rezafungin side effects

37.7% of rezafungin adverse event reports involve female patients and 36.9% involve male patients. The largest age group is adult at 61%. These figures reflect who reports side effects, not underlying risk.

Sex

Female37.7%
Male36.9%
Unknown25.4%

Age group

< 20.0%
2–113.3%
12–170.0%
18–6460.7%
65+36.1%

What is rezafungin used for

Conditions and purposes for which patients were taking rezafungin when the adverse event was reported.

Antifungal ProphylaxisAspergillus InfectionBronchopulmonary AspergillosisCandida InfectionCandida OsteomyelitisComplex Regional Pain SyndromeCoughDevice Related InfectionDiabetes MellitusDiverticulitis Intestinal PerforatedDrug ResistanceEmphysemaFungaemiaFungal InfectionHaematological Infection

Showing 15 of 55 indications

Rezafungin brand names and reporting trend

Rezafungin is sold under the brand name Rezzayo.

Brand names

Rezzayo80

Quarterly reports (20222025)

202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking rezafungin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.