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Reserpine Side Effects

The most commonly reported side effects of reserpine include hypertension, blood pressure increased, and headache, based on 538 FDA adverse event reports from 2004 to 2025.

Reserpine side effects

Percentages show how often each reaction appears relative to total reports for reserpine.

1
Hypertension7.4%40
2
Blood Pressure Increased5.8%31
3
Headache5.6%30
4
Dizziness4.5%24
5
Pneumonia4.3%23
6
Malaise4.3%23
7
Fatigue4.1%22
8
Dyspnoea3.9%21
9
Diarrhoea3.2%17
10
Pain3.2%17
11
Fall3.0%16
12
Pyrexia2.8%15
13
Decreased Appetite2.8%15
14
Blood Pressure Decreased2.8%15
15
Shock2.8%15

These are voluntary reports and do not establish that reserpine caused these reactions.

Report severity

91.4%Serious492 reports
45.7%Hospitalizations246 reports
17.3%Fatal93 reports

Seriousness is determined by the reporter, not by OpenClaim.

Reserpine drug interactions

Other drugs that appear in adverse event reports alongside reserpine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Hydralazine-hydrochloride29.7%160
2
Valsartan11.7%63
3
Amlodipine5.9%32
4
Hydrochlorothiazide5.6%30
5
Metformin5.0%27
6
Enalapril-maleate4.8%26
7
Atenolol3.5%19
8
Adalimumab3.0%16
9
Azacitidine3.0%16
10
Losartan-potassium3.0%16
11
Methyldopa3.0%16
12
Aspirin2.8%15
13
Simvastatin2.8%15
14
Spironolactone2.4%13
15
Insulin2.2%12

Taken alongside

1
Hydralazine-hydrochloride33.1%178
2
Furosemide13.0%70
3
Hydrochlorothiazide8.4%45
4
Aspirin8.4%45
5
Amlodipine7.6%41
6
Omeprazole7.2%39
7
Meropenem6.7%36
8
Acetaminophen5.9%32
9
Prednisone5.4%29
10
Ergocalciferol5.4%29
11
Hydroflumethiazide5.2%28
12
Granisetron5.2%28
13
Vancomycin5.0%27
14
Atorvastatin-calcium5.0%27
15
Insulin5.0%27

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports reserpine side effects

51.7% of reserpine adverse event reports involve female patients and 43.1% involve male patients. The largest age group is elderly at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female51.7%
Male43.1%
Unknown5.2%

Age group

< 21.6%
2–110.5%
12–171.0%
18–6438.1%
65+58.8%

What is reserpine used for

Conditions and purposes for which patients were taking reserpine when the adverse event was reported.

AgitationAnticoagulant TherapyArrhythmiaBacterial InfectionBlood PressureBlood Pressure AbnormalBlood Pressure IncreasedCardiac DisorderCardiac FailureCardiomegalyCardiomyopathyCardiovascular Disorder NosCerebrovascular AccidentColitisColitis Ulcerative

Showing 15 of 71 indications

Reserpine brand names and reporting trend

Reserpine is sold under the brand name Hydrap-es.

Brand names

Hydrap-es157

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking reserpine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.