OpenClaim

Regadenoson Side Effects

The most commonly reported side effects of regadenoson include nausea, dyspnoea, and injection site extravasation, based on 4,722 FDA adverse event reports from 2008 to 2025.

Regadenoson side effects

Percentages show how often each reaction appears relative to total reports for regadenoson.

1
Nausea9.0%423
2
Dyspnoea7.7%364
3
Injection Site Extravasation7.6%360
4
Vomiting6.7%318
5
Hypotension5.9%278
6
Headache5.7%270
7
Cardiac Arrest5.5%260
8
Seizure5.3%251
9
Dizziness5.0%235
10
Chest Pain4.4%208
11
Blood Pressure Decreased4.1%192
12
Tremor3.6%170
13
Bradycardia3.6%168
14
Loss Of Consciousness3.3%157
15
Diarrhoea2.9%136

These are voluntary reports and do not establish that regadenoson caused these reactions.

Report severity

55.7%Serious2,631 reports
10.5%Hospitalizations494 reports
2.8%Fatal130 reports

Seriousness is determined by the reporter, not by OpenClaim.

Regadenoson drug interactions

Other drugs that appear in adverse event reports alongside regadenoson. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aminophylline1.1%54
2
Technetium-tc-99m-sestamibi-kit0.9%41
3
Technetium-tc-99m-tetrofosmin-kit0.5%22
4
Nitroglycerin0.4%19
5
Rubidium-chloride-rb-820.3%15
6
Esomeprazole0.3%12
7
Lansoprazole0.2%9
8
Omeprazole0.2%9
9
Acetaminophen0.1%7
10
Aspirin0.1%7
11
Hydrocodone0.1%6
12
Metoprolol0.1%6
13
Perflutren0.1%6
14
Dupilumab0.1%6
15
Technetium-tc-99m-sodium-pertechnetate-generator0.1%5

Taken alongside

1
Aspirin7.2%338
2
Atorvastatin-calcium4.3%203
3
Metoprolol4.3%201
4
Acetaminophen3.5%165
5
Amlodipine3.3%158
6
Lisinopril3.3%157
7
Albuterol2.7%126
8
Furosemide2.6%125
9
Nitroglycerin2.6%124
10
Levothyroxine-sodium2.6%121
11
Omeprazole2.5%119
12
Ergocalciferol2.4%111
13
Simvastatin2.3%108
14
Metformin2.3%108
15
Hydrochlorothiazide2.3%107

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports regadenoson side effects

48.2% of regadenoson adverse event reports involve female patients and 32.3% involve male patients. The largest age group is elderly at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female48.2%
Male32.3%
Unknown19.5%

Age group

< 2<0.1%
2–11<0.1%
12–170.0%
18–6437.2%
65+62.7%

What is regadenoson used for

Conditions and purposes for which patients were taking regadenoson when the adverse event was reported.

AbasiaAcute Coronary SyndromeAcute Myocardial InfarctionAngina PectorisAngina UnstableAngiogramAortic ArteriosclerosisArrhythmiaAtrial FibrillationAtrioventricular BlockAcute Myocardial InfarctionArteriosclerosis Coronary ArteryAtrial FibrillationBlood Pressure IncreasedBundle Branch Block Right

Showing 15 of 129 indications

Regadenoson brand names and reporting trend

Regadenoson is sold under the brand name Lexiscan.

Brand names

Lexiscan797

Quarterly reports (20082025)

20082010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking regadenoson with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.