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Rasagiline Side Effects

The most commonly reported side effects of rasagiline include fall, hallucination, and dyskinesia, based on 11,047 FDA adverse event reports from 2006 to 2025. 6.2% of reports found the drug to be ineffective.

Rasagiline side effects

Percentages show how often each reaction appears relative to total reports for rasagiline.

1
Fall9.0%991
2
Hallucination7.9%871
3
Dyskinesia6.4%705
4
Drug Ineffective6.2%685
5
Death5.3%587
6
Tremor5.3%587
7
Dizziness5.3%583
8
Parkinson^s Disease4.9%536
9
Confusional State4.3%477
10
Gait Disturbance4.2%464
11
Somnolence4.1%454
12
Nausea4.0%440
13
Fatigue3.8%422
14
Constipation3.5%386
15
Insomnia3.0%333

These are voluntary reports and do not establish that rasagiline caused these reactions.

Report severity

66.7%Serious7,363 reports
32.6%Hospitalizations3,606 reports
11.0%Fatal1,210 reports

Seriousness is determined by the reporter, not by OpenClaim.

Rasagiline drug interactions

Other drugs that appear in adverse event reports alongside rasagiline. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Levodopa26.7%2,946
2
Carbidopa21.9%2,416
3
Pimavanserin11.1%1,223
4
Pramipexole-dihydrochloride5.1%562
5
Amantadine4.7%522
6
Rotigotine4.6%509
7
Ropinirole-hydrochloride4.6%503
8
Entacapone4.4%488
9
Apomorphine-hydrochloride4.1%455
10
Istradefylline3.4%371
11
Droxidopa1.8%197
12
Quetiapine-fumarate1.2%133
13
Opicapone1.0%111
14
Pregabalin0.8%93
15
Metformin0.8%92

Taken alongside

1
Levodopa41.6%4,600
2
Carbidopa39.8%4,398
3
Entacapone12.2%1,345
4
Amantadine11.6%1,283
5
Aspirin11.4%1,257
6
Pramipexole-dihydrochloride10.9%1,199
7
Ergocalciferol9.9%1,090
8
Ropinirole-hydrochloride8.6%955
9
Atorvastatin-calcium7.9%877
10
Levothyroxine-sodium7.5%826
11
Clonazepam7.0%772
12
Omeprazole6.3%691
13
Quetiapine-fumarate6.1%678
14
Acetaminophen6.0%666
15
Tamsulosin-hydrochloride5.8%637

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports rasagiline side effects

36.9% of rasagiline adverse event reports involve female patients and 54.8% involve male patients. The largest age group is elderly at 76%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.9%
Male54.8%
Unknown8.3%

Age group

< 20.1%
2–11<0.1%
12–17<0.1%
18–6424.2%
65+75.6%

What is rasagiline used for

Conditions and purposes for which patients were taking rasagiline when the adverse event was reported.

Adjuvant TherapyAmnesiaAntibiotic TherapyAnxietyArrhythmiaAstheniaAdjuvant TherapyAdverse Drug ReactionAutoimmune HypothyroidismBladder DisorderBlood CholesterolBlood Pressure AbnormalBradykinesiaBehaviour DisorderCognitive Disorder

Showing 15 of 94 indications

Rasagiline brand names and reporting trend

Rasagiline is sold under the brand name Azilect.

Brand names

Azilect67

Quarterly reports (20062025)

20062010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking rasagiline with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.