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Protirelin Side Effects

The most commonly reported side effects of protirelin include pituitary haemorrhage, nausea, and drug intolerance, based on 18 FDA adverse event reports from 2006 to 2023.

Protirelin side effects

Percentages show how often each reaction appears relative to total reports for protirelin.

1
Pituitary Haemorrhage27.8%5
2
Nausea16.7%3
3
Drug Intolerance11.1%2
4
Injection Site Abscess11.1%2
5
Stevens-johnson Syndrome11.1%2
6
Pyrexia11.1%2
7
Diabetes Insipidus11.1%2
8
Injection Site Extravasation5.6%1
9
Skin Graft5.6%1
10
Infusion Site Extravasation5.6%1
11
Cold Sweat5.6%1
12
Disorientation5.6%1
13
Hemiplegia5.6%1
14
Loss Of Consciousness5.6%1
15
Hypoglycaemia5.6%1

These are voluntary reports and do not establish that protirelin caused these reactions.

Report severity

94.4%Serious17 reports
61.1%Hospitalizations11 reports
5.6%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Protirelin drug interactions

Other drugs that appear in adverse event reports alongside protirelin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Insulin22.2%4
2
Hydrocortisone22.2%4
3
Midazolam11.1%2
4
Meglumine5.6%1
5
Levodopa5.6%1
6
Abobotulinumtoxina5.6%1
7
Dexamethasone5.6%1
8
Prednisolone5.6%1
9
Clonazepam5.6%1
10
Calcium5.6%1
11
Levetiracetam5.6%1
12
Apremilast5.6%1
13
Apixaban5.6%1
14
Topiramate5.6%1
15
Phenobarbital-sodium5.6%1

Taken alongside

1
Lidocaine16.7%3
2
Gonadorelin11.1%2
3
Insulin11.1%2
4
Levothyroxine-sodium11.1%2
5
Progesterone5.6%1
6
Dexamethasone5.6%1
7
Calcium5.6%1
8
Acetaminophen5.6%1
9
Triamcinolone5.6%1
10
Omeprazole5.6%1
11
Hydrochlorothiazide5.6%1
12
Vitamin-e5.6%1
13
Fluocinolone-acetonide5.6%1
14
Rosuvastatin5.6%1
15
Fluticasone5.6%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports protirelin side effects

44.4% of protirelin adverse event reports involve female patients and 55.6% involve male patients. The largest age group is adult at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.4%
Male55.6%
Unknown0.0%

Age group

< 25.6%
2–1116.7%
12–1711.1%
18–6455.6%
65+11.1%

What is protirelin used for

Conditions and purposes for which patients were taking protirelin when the adverse event was reported.

Diagnostic ProcedureEncephalitis AutoimmuneEpilepsyProduct Used For Unknown IndicationProduct Used For Unknown IndicationRhinorrhoea

Protirelin brand names and reporting trend

Protirelin is sold under the brand name Thyrel Trh.

Brand names

Thyrel Trh19

Quarterly reports (20062023)

20062023

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking protirelin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.