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Propiomazine Side Effects

The most commonly reported side effects of propiomazine include intentional overdose, intentional self-injury, and toxicity to various agents, based on 616 FDA adverse event reports from 2004 to 2025.

Propiomazine side effects

Percentages show how often each reaction appears relative to total reports for propiomazine.

1
Intentional Overdose42.4%261
2
Intentional Self-injury35.4%218
3
Toxicity To Various Agents22.9%141
4
Suicide Attempt13.1%81
5
Depressed Level Of Consciousness8.3%51
6
Fatigue7.1%44
7
Suicidal Ideation6.8%42
8
Tachycardia5.4%33
9
Overdose5.0%31
10
Somnolence3.9%24
11
Loss Of Consciousness3.6%22
12
Cardiac Arrest3.4%21
13
Abdominal Pain2.9%18
14
Dizziness2.8%17
15
Mydriasis2.8%17

These are voluntary reports and do not establish that propiomazine caused these reactions.

Report severity

99.5%Serious613 reports
67.7%Hospitalizations417 reports
14.8%Fatal91 reports

Seriousness is determined by the reporter, not by OpenClaim.

Propiomazine drug interactions

Other drugs that appear in adverse event reports alongside propiomazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sertraline-hydrochloride18.0%111
2
Lisdexamfetamine-dimesylate15.6%96
3
Quetiapine-fumarate13.3%82
4
Trimeprazine-tartrate9.6%59
5
Venlafaxine9.3%57
6
Fluoxetine-hydrochloride9.3%57
7
Zolpidem-tartrate8.3%51
8
Eszopiclone8.0%49
9
Olanzapine7.8%48
10
Mirtazapine7.0%43
11
Citalopram-hydrobromide6.5%40
12
Acetaminophen6.5%40
13
Diazepam6.3%39
14
Oxazepam5.0%31
15
Lamotrigine5.0%31

Taken alongside

1
Acetaminophen9.1%56
2
Eszopiclone6.3%39
3
Omeprazole6.0%37
4
Diazepam3.9%24
5
Oxazepam3.6%22
6
Aspirin3.4%21
7
Zolpidem-tartrate3.4%21
8
Amitriptyline-hydrochloride3.1%19
9
Levothyroxine-sodium2.8%17
10
Hydroxyzine2.6%16
11
Citalopram-hydrobromide2.6%16
12
Sumatriptan2.6%16
13
Furosemide2.4%15
14
Metoprolol2.4%15
15
Sertraline-hydrochloride2.3%14

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports propiomazine side effects

62.7% of propiomazine adverse event reports involve female patients and 32.3% involve male patients. The largest age group is adult at 77%. These figures reflect who reports side effects, not underlying risk.

Sex

Female62.7%
Male32.3%
Unknown5.0%

Age group

< 20.0%
2–110.2%
12–1711.6%
18–6476.8%
65+11.4%

What is propiomazine used for

Conditions and purposes for which patients were taking propiomazine when the adverse event was reported.

AnxietyCoughCompleted SuicideCoughDrug Use For Unknown IndicationDepressionIncreased Upper Airway SecretionInsomniaInfluenzaInsomniaNasopharyngitisNauseaObsessive-compulsive DisorderOverdoseProduct Used For Unknown Indication

Showing 15 of 25 indications

Propiomazine brand names and reporting trend

Propiomazine is sold under the brand name Largon.

Brand names

Largon623

Quarterly reports (20042025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking propiomazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.