OpenClaim

Prasugrel Side Effects

The most commonly reported side effects of prasugrel include myocardial infarction, gastrointestinal haemorrhage, and dyspnoea, based on 12,395 FDA adverse event reports from 2009 to 2025. 2.3% of reports found the drug to be ineffective.

Prasugrel side effects

Percentages show how often each reaction appears relative to total reports for prasugrel.

1
Myocardial Infarction4.7%582
2
Gastrointestinal Haemorrhage3.8%473
3
Dyspnoea3.8%470
4
Haemorrhage3.5%429
5
Chest Pain3.4%423
6
Contusion3.3%415
7
Fatigue2.9%365
8
Off Label Use2.9%363
9
Nausea2.9%357
10
Dizziness2.8%343
11
Drug Ineffective2.3%281
12
Epistaxis2.2%275
13
Headache2.2%269
14
Diarrhoea2.1%263
15
Asthenia2.0%254

These are voluntary reports and do not establish that prasugrel caused these reactions.

Report severity

76.8%Serious9,520 reports
40.7%Hospitalizations5,047 reports
9.0%Fatal1,114 reports

Seriousness is determined by the reporter, not by OpenClaim.

Prasugrel drug interactions

Other drugs that appear in adverse event reports alongside prasugrel. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aspirin8.1%1,008
2
Atorvastatin-calcium2.2%277
3
Rivaroxaban2.2%271
4
Gemfibrozil1.6%202
5
Heparin1.6%199
6
Ticagrelor1.6%199
7
Rosuvastatin1.6%193
8
Evolocumab1.6%193
9
Niacin1.4%168
10
Clopidogrel-bisulfate1.3%167
11
Pantoprazole-sodium1.3%155
12
Esomeprazole1.2%147
13
Adalimumab1.2%143
14
Omeprazole1.1%136
15
Valsartan1.0%121

Taken alongside

1
Aspirin40.1%4,969
2
Atorvastatin-calcium15.8%1,957
3
Metoprolol14.2%1,761
4
Rosuvastatin9.7%1,200
5
Lisinopril8.7%1,079
6
Carvedilol8.3%1,034
7
Amlodipine8.2%1,017
8
Furosemide7.7%955
9
Metformin7.5%926
10
Nitroglycerin7.1%885
11
Insulin6.5%811
12
Simvastatin5.7%711
13
Omeprazole5.7%708
14
Acetaminophen5.6%691
15
Pantoprazole-sodium5.6%689

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports prasugrel side effects

32.4% of prasugrel adverse event reports involve female patients and 60.8% involve male patients. The largest age group is elderly at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female32.4%
Male60.8%
Unknown6.7%

Age group

< 2<0.1%
2–11<0.1%
12–17<0.1%
18–6449.8%
65+50.0%

What is prasugrel used for

Conditions and purposes for which patients were taking prasugrel when the adverse event was reported.

Acute Coronary SyndromeAcute Febrile Neutrophilic DermatosisAcute Myocardial InfarctionAcute Pulmonary OedemaAdverse Drug ReactionAnalgesic Intervention Supportive TherapyAneurysmAneurysm RepairAngina PectorisAngina UnstableAngiogramAngiogram AbnormalAngiopathyAngioplastyAnti-platelet Antibody

Showing 15 of 281 indications

Prasugrel brand names and reporting trend

Prasugrel is sold under the brand name Prasugrel Hydrochloride.

Brand names

Prasugrel Hydrochloride1

Quarterly reports (20092025)

200920122016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking prasugrel with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.