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Prabotulinumtoxina Side Effects

The most commonly reported side effects of prabotulinumtoxina include off label use, therapeutic product effect decreased, and drug effect less than expected, based on 3,284 FDA adverse event reports from 2019 to 2025. 41.0% of reports found the drug to be ineffective.

#1 Reported: Off Label UseAll side effects ↓Top Co-Medication: OnabotulinumtoxinaDrug interactions ↓98% of Reports Are AdultDemographics ↓

Prabotulinumtoxina side effects

Percentages show how often each reaction appears relative to total reports for prabotulinumtoxina.

1
Drug Ineffective41.0%1,346
2
Off Label Use33.6%1,103
3
Therapeutic Product Effect Decreased21.7%714
4
Drug Effect Less Than Expected10.8%354
5
Headache4.8%157
6
Injection Site Pain3.1%101
7
Injection Site Swelling2.8%91
8
Patient Dissatisfaction With Treatment2.8%91
9
Inappropriate Schedule Of Product Administration2.2%72
10
Eyelid Ptosis1.9%63
11
Injection Site Erythema1.9%62
12
Product Preparation Issue1.7%57
13
Injection Site Pruritus1.4%45
14
Product Storage Error1.2%39
15
Dizziness1.1%37

These are voluntary reports and do not establish that prabotulinumtoxina caused these reactions.

Report severity

1.6%Serious53 reports
0.6%Hospitalizations21 reports
<0.1%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Prabotulinumtoxina drug interactions

Other drugs that appear in adverse event reports alongside prabotulinumtoxina. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Onabotulinumtoxina0.7%24
2
Incobotulinumtoxina0.4%14
3
Abobotulinumtoxina0.2%8
4
Teprotumumab-trbw<0.1%1
5
Letibotulinumtoxina-wlbg<0.1%1
6
Calcium-oxybate<0.1%1
7
Magnesium-oxybate<0.1%1
8
Potassium-oxybate<0.1%1
9
Sodium-oxybate<0.1%1

Taken alongside

1
Onabotulinumtoxina1.2%38
2
Ergocalciferol0.3%11
3
Levothyroxine-sodium0.3%10
4
Abobotulinumtoxina0.3%10
5
Ascorbic-acid0.2%6
6
Incobotulinumtoxina0.2%5
7
Fish0.2%5
8
Dextroamphetamine0.1%4
9
Calcium0.1%4
10
Loratadine0.1%4
11
Acyclovir<0.1%3
12
Amphetamine<0.1%3
13
Fexofenadine-hydrochloride<0.1%3
14
Cetirizine-hydrochloride<0.1%3
15
Sertraline-hydrochloride<0.1%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports prabotulinumtoxina side effects

34.9% of prabotulinumtoxina adverse event reports involve female patients and 3.6% involve male patients. The largest age group is adult at 98%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.9%
Male3.6%
Unknown61.5%

Age group

< 2<0.1%
2–11<0.1%
12–170.0%
18–6498.2%
65+1.7%

What is prabotulinumtoxina used for

Conditions and purposes for which patients were taking prabotulinumtoxina when the adverse event was reported.

BruxismCardiac MurmurExcessive Gingival DisplayFace LiftFace LiftHyperhidrosisOff Label UseOff Label UseProduct Use In Unapproved IndicationProduct Used For Unknown IndicationPersonal HygieneProduct Use In Unapproved IndicationProduct Used For Unknown IndicationSkin Cosmetic ProcedureSkin Wrinkling

Showing 15 of 20 indications

Prabotulinumtoxina brand names and reporting trend

Quarterly reports (2019–2025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking prabotulinumtoxina with another medication?

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