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Potassium Citrate Side Effects

The most commonly reported side effects of potassium citrate include fatigue, diarrhoea, and nausea, based on 5,764 FDA adverse event reports from 2004 to 2025. 7.2% of reports found the drug to be ineffective.

Potassium Citrate side effects

Percentages show how often each reaction appears relative to total reports for potassium citrate.

1
Drug Ineffective7.2%413
2
Fatigue6.0%348
3
Diarrhoea5.6%321
4
Nausea5.5%319
5
Pain5.0%291
6
Off Label Use4.4%255
7
Nephrolithiasis4.3%250
8
Dyspnoea3.9%226
9
Dizziness3.8%217
10
Headache3.5%202
11
Fall3.5%201
12
Vomiting2.9%167
13
Pneumonia2.8%161
14
Asthenia2.7%155
15
Urinary Tract Infection2.5%144

These are voluntary reports and do not establish that potassium citrate caused these reactions.

Report severity

61.4%Serious3,537 reports
32.2%Hospitalizations1,854 reports
6.1%Fatal350 reports

Seriousness is determined by the reporter, not by OpenClaim.

Potassium Citrate drug interactions

Other drugs that appear in adverse event reports alongside potassium citrate. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate5.4%310
2
Lenalidomide4.1%235
3
Adalimumab4.0%233
4
Tiopronin3.2%185
5
Furosemide2.1%121
6
Omeprazole1.6%94
7
Esomeprazole1.5%85
8
Apixaban1.5%84
9
Pantoprazole-sodium1.4%79
10
Potassium-chloride1.3%76
11
Prednisone1.2%72
12
Dexamethasone1.2%72
13
Allopurinol1.2%67
14
Etanercept1.1%66
15
Ruxolitinib1.1%66

Taken alongside

1
Ergocalciferol23.1%1,329
2
Aspirin21.5%1,241
3
Acetaminophen18.2%1,048
4
Levothyroxine-sodium15.8%910
5
Atorvastatin-calcium14.5%833
6
Omeprazole14.4%830
7
Allopurinol13.1%754
8
Amlodipine12.6%726
9
Metoprolol12.5%722
10
Furosemide12.3%707
11
Albuterol11.8%679
12
Pantoprazole-sodium11.2%647
13
Hydrochlorothiazide11.2%644
14
Metformin11.2%644
15
Gabapentin10.7%618

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports potassium citrate side effects

47.1% of potassium citrate adverse event reports involve female patients and 45.3% involve male patients. The largest age group is elderly at 48%. These figures reflect who reports side effects, not underlying risk.

Sex

Female47.1%
Male45.3%
Unknown7.6%

Age group

< 20.8%
2–111.9%
12–172.0%
18–6447.6%
65+47.7%

What is potassium citrate used for

Conditions and purposes for which patients were taking potassium citrate when the adverse event was reported.

11-beta-hydroxylase DeficiencyAbdominal Pain UpperAcidosisAdjuvant TherapyAlkaptonuriaAmino Acid LevelAnaemiaAntacid TherapyArrhythmiaAcidosisAmino Acid Metabolism DisorderAsthmaAutoimmune ThyroiditisBartter^s SyndromeBenign Prostatic Hyperplasia

Showing 15 of 205 indications

Potassium Citrate brand names and reporting trend

Potassium Citrate is sold under the brand name Urocit-k.

Brand names

Urocit-k5,599

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking potassium citrate with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.