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Polytetrafluoroethylene Side Effects

The most commonly reported side effects of polytetrafluoroethylene include insomnia, flushing, and completed suicide, based on 55 FDA adverse event reports from 2005 to 2025. 7.3% of reports found the drug to be ineffective.

Polytetrafluoroethylene side effects

Percentages show how often each reaction appears relative to total reports for polytetrafluoroethylene.

1
Insomnia9.1%5
2
Drug Ineffective7.3%4
3
Flushing5.5%3
4
Completed Suicide5.5%3
5
Toxicity To Various Agents5.5%3
6
Rash5.5%3
7
Fatigue5.5%3
8
Blood Glucose Increased3.6%2
9
Pharmaceutical Product Complaint3.6%2
10
Vomiting3.6%2
11
Middle Insomnia3.6%2
12
Completed Suicide3.6%2
13
Nausea3.6%2
14
Drug Toxicity3.6%2
15
Fatigue3.6%2

These are voluntary reports and do not establish that polytetrafluoroethylene caused these reactions.

Report severity

61.8%Serious34 reports
30.9%Hospitalizations17 reports
16.4%Fatal9 reports

Seriousness is determined by the reporter, not by OpenClaim.

Polytetrafluoroethylene drug interactions

Other drugs that appear in adverse event reports alongside polytetrafluoroethylene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Perfluoropolymethylisopropyl-ether16.4%9
2
Eszopiclone10.9%6
3
Insulin5.5%3
4
Adalimumab5.5%3
5
Pioglitazone-hydrochloride3.6%2
6
Acetaminophen3.6%2
7
Amlodipine3.6%2
8
Albuterol3.6%2
9
Potassium-chloride3.6%2
10
Niacin3.6%2
11
Tiotropium-bromide3.6%2
12
Ciprofloxacin3.6%2
13
Sodium-sulfate3.6%2
14
Venlafaxine3.6%2
15
Bupropion3.6%2

Taken alongside

1
Perfluoropolymethylisopropyl-ether81.8%45
2
Acetaminophen14.5%8
3
Atorvastatin-calcium10.9%6
4
Insulin9.1%5
5
Gabapentin9.1%5
6
Ergocalciferol9.1%5
7
Prednisone9.1%5
8
Calcium7.3%4
9
Ipratropium-bromide7.3%4
10
Metformin7.3%4
11
Terbutaline-sulfate7.3%4
12
Furosemide5.5%3
13
Citalopram-hydrobromide5.5%3
14
Albuterol5.5%3
15
Ibuprofen5.5%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports polytetrafluoroethylene side effects

54.5% of polytetrafluoroethylene adverse event reports involve female patients and 40.0% involve male patients. The largest age group is adult at 69%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.5%
Male40.0%
Unknown5.5%

Age group

< 20.0%
2–112.8%
12–170.0%
18–6469.4%
65+27.8%

What is polytetrafluoroethylene used for

Conditions and purposes for which patients were taking polytetrafluoroethylene when the adverse event was reported.

Blood Pressure MeasurementEczemaIll-defined DisorderPainProduct Used For Unknown IndicationPsoriasisProduct Used For Unknown IndicationRosaceaSuicide AttemptType 2 Diabetes MellitusType 2 Diabetes Mellitus

Polytetrafluoroethylene brand names and reporting trend

Polytetrafluoroethylene is sold under the brand name Skin Exposure Reduction Paste Against Chemical Warfare Agents.

Brand names

Skin Exposure Reduction Paste Against Chemical Warfare Agents1

Quarterly reports (20052025)

2005201020152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking polytetrafluoroethylene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.