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Polyestradiol Side Effects

The most commonly reported side effects of polyestradiol include bone disorder, osteonecrosis, and cough, based on 6 FDA adverse event reports from 2005 to 2019.

Polyestradiol side effects

Percentages show how often each reaction appears relative to total reports for polyestradiol.

1
Bone Disorder16.7%1
2
Osteonecrosis16.7%1
3
Cough16.7%1
4
Dysphonia16.7%1
5
Nausea16.7%1
6
Paresis16.7%1
7
Asthenia16.7%1
8
Blood Creatinine Increased16.7%1
9
Blood Urea Increased16.7%1
10
Haemoglobin Decreased16.7%1
11
Hydronephrosis16.7%1
12
Obstructive Uropathy16.7%1
13
Oedema Peripheral16.7%1
14
Weight Decreased16.7%1
15
Rectal Ulcer16.7%1

These are voluntary reports and do not establish that polyestradiol caused these reactions.

Report severity

100.0%Serious6 reports
50.0%Hospitalizations3 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Polyestradiol drug interactions

Other drugs that appear in adverse event reports alongside polyestradiol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Zoledronic-acid33.3%2
2
Gemcitabine16.7%1
3
Sunitinib-malate16.7%1
4
Prednisolone16.7%1
5
Enasidenib-mesylate16.7%1
6
Mycophenolate16.7%1
7
Vancomycin16.7%1
8
Busulfan16.7%1
9
Cytarabine16.7%1
10
Thiotepa16.7%1
11
Azacitidine16.7%1
12
Ceftazidime16.7%1
13
Metronidazole16.7%1
14
Ondansetron16.7%1
15
Deoxycholic-acid16.7%1

Taken alongside

1
Gabapentin33.3%2
2
Oxycodone33.3%2
3
Omeprazole33.3%2
4
Diclofenac16.7%1
5
Prednisone16.7%1
6
Bicalutamide16.7%1
7
Prednisolone16.7%1
8
Docetaxel16.7%1
9
Lansoprazole16.7%1
10
Goserelin16.7%1
11
Acetaminophen16.7%1
12
Enalapril-maleate16.7%1
13
Zolpidem-tartrate16.7%1
14
Atenolol16.7%1
15
Simvastatin16.7%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports polyestradiol side effects

33.3% of polyestradiol adverse event reports involve female patients and 66.7% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female33.3%
Male66.7%
Unknown0.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6440.0%
65+60.0%

What is polyestradiol used for

Conditions and purposes for which patients were taking polyestradiol when the adverse event was reported.

Bone Marrow Conditioning RegimenProduct Used For Unknown IndicationProstate Cancer

Polyestradiol brand names and reporting trend

Polyestradiol is sold under the brand name Estradurin.

Brand names

Estradurin1

Quarterly reports (20052019)

200520122019

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking polyestradiol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.