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Plozasiran Side Effects

The most commonly reported side effects of plozasiran include pyrexia, abdominal pain, and pneumonia, based on 20 FDA adverse event reports from 2007 to 2024.

Plozasiran side effects

Percentages show how often each reaction appears relative to total reports for plozasiran.

1
Pyrexia15.0%3
2
Abdominal Pain15.0%3
3
Pneumonia15.0%3
4
Acute Kidney Injury10.0%2
5
International Normalised Ratio Increased10.0%2
6
Cough10.0%2
7
Diarrhoea10.0%2
8
Asthenia10.0%2
9
Soft Tissue Haemorrhage10.0%2
10
Anaemia5.0%1
11
Blood Alkaline Phosphatase Increased5.0%1
12
Blood Bilirubin Increased5.0%1
13
Electrocardiogram Change5.0%1
14
Jaundice5.0%1
15
Pyrexia5.0%1

These are voluntary reports and do not establish that plozasiran caused these reactions.

Report severity

90.0%Serious18 reports
70.0%Hospitalizations14 reports
20.0%Fatal4 reports

Seriousness is determined by the reporter, not by OpenClaim.

Plozasiran drug interactions

Other drugs that appear in adverse event reports alongside plozasiran. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Enoxaparin-sodium10.0%2
2
Aspirin10.0%2
3
Rivaroxaban10.0%2
4
Venetoclax10.0%2
5
Azacitidine10.0%2
6
Carboplatin10.0%2
7
Selinexor10.0%2
8
Amoxicillin5.0%1
9
Clavulanate-potassium5.0%1
10
Warfarin5.0%1
11
Apixaban5.0%1
12
Ipilimumab5.0%1
13
Nivolumab5.0%1
14
Hexocyclium-methylsulfate5.0%1
15
Ofatumumab5.0%1

Taken alongside

1
Prednisone40.0%8
2
Hydrocortisone25.0%5
3
Albuterol25.0%5
4
Aspirin25.0%5
5
Atorvastatin-calcium25.0%5
6
Pentazocine20.0%4
7
Losartan-potassium20.0%4
8
Insulin15.0%3
9
Methylprednisolone15.0%3
10
Esomeprazole15.0%3
11
Acetaminophen15.0%3
12
Oxycodone15.0%3
13
Heparin15.0%3
14
Filgrastim15.0%3
15
Spironolactone10.0%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports plozasiran side effects

55.0% of plozasiran adverse event reports involve female patients and 40.0% involve male patients. The largest age group is elderly at 83%. These figures reflect who reports side effects, not underlying risk.

Sex

Female55.0%
Male40.0%
Unknown5.0%

Age group

< 20.0%
2–115.6%
12–170.0%
18–6411.1%
65+83.3%

What is plozasiran used for

Conditions and purposes for which patients were taking plozasiran when the adverse event was reported.

Antiallergic TherapyChronic Obstructive Pulmonary DiseaseCoughChronic Obstructive Pulmonary DiseaseCoughDyspnoeaProduct Used For Unknown IndicationSinusitis

Plozasiran brand names and reporting trend

Plozasiran is sold under the brand name Redemplo.

Brand names

Redemplo18

Quarterly reports (20072024)

200720152024

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking plozasiran with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.