OpenClaim

Plerixafor Side Effects

The most commonly reported side effects of plerixafor include febrile neutropenia, off label use, and diarrhoea, based on 1,454 FDA adverse event reports from 2008 to 2025. 2.5% of reports found the drug to be ineffective.

#1 Reported: Febrile NeutropeniaAll side effects ↓Top Co-Medication: FilgrastimDrug interactions ↓63% of Reports Are AdultDemographics ↓

Plerixafor side effects

Percentages show how often each reaction appears relative to total reports for plerixafor.

1
Febrile Neutropenia8.5%123
2
Off Label Use8.3%121
3
Diarrhoea6.1%88
4
Mucosal Inflammation5.1%74
5
Pyrexia5.0%72
6
Thrombocytopenia4.5%66
7
Nausea4.2%61
8
Plasma Cell Myeloma4.1%60
9
Death3.6%52
10
Neutropenia3.2%47
11
Pneumonia3.1%45
12
Acute Kidney Injury3.0%44
13
Dyspnoea3.0%43
14
Infection2.9%42
15
Vomiting2.8%41

These are voluntary reports and do not establish that plerixafor caused these reactions.

Report severity

79.2%Serious1,151 reports
32.5%Hospitalizations473 reports
16.5%Fatal240 reports

Seriousness is determined by the reporter, not by OpenClaim.

Plerixafor drug interactions

Other drugs that appear in adverse event reports alongside plerixafor. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Filgrastim20.2%294
2
Lenalidomide18.9%275
3
Dexamethasone8.8%128
4
Cytarabine8.4%122
5
Cyclophosphamide7.6%111
6
Fludarabine-phosphate7.4%107
7
Etoposide6.5%95
8
Busulfan5.8%85
9
Melphalan5.6%81
10
Bortezomib5.2%76
11
Rituximab5.1%74
12
Pegfilgrastim4.7%69
13
Pomalidomide2.9%42
14
Daratumumab2.6%38
15
Doxorubicin-hydrochloride2.5%37

Taken alongside

1
Filgrastim22.6%328
2
Dexamethasone17.1%248
3
Acyclovir14.6%212
4
Ondansetron9.6%140
5
Acetaminophen9.5%138
6
Melphalan7.5%109
7
Bortezomib7.1%103
8
Aspirin7.0%102
9
Cyclophosphamide6.5%94
10
Omeprazole5.8%84
11
Etoposide5.7%83
12
Fluconazole5.6%82
13
Ergocalciferol5.2%75
14
Pantoprazole-sodium5.1%74
15
Lorazepam4.9%71

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports plerixafor side effects

36.1% of plerixafor adverse event reports involve female patients and 40.6% involve male patients. The largest age group is adult at 63%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.1%
Male40.6%
Unknown23.2%

Age group

< 20.9%
2–119.6%
12–172.5%
18–6462.7%
65+24.3%

What is plerixafor used for

Conditions and purposes for which patients were taking plerixafor when the adverse event was reported.

Acute LeukaemiaAcute Lymphocytic LeukaemiaAcute Monocytic LeukaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RecurrentAcute Myeloid LeukemiaAdenocarcinomaAmyloidosisApheresisAutologous Haematopoietic Stem Cell TransplantAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RefractoryAdverse Drug ReactionAllogenic Stem Cell Transplantation

Showing 15 of 124 indications

Plerixafor brand names and reporting trend

Plerixafor is sold under the brand name Mozobil.

Brand names

Mozobil844

Quarterly reports (2008–2025)

2010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking plerixafor with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

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