The most commonly reported side effects of pirfenidone include death, nausea, and fatigue, based on 40,170 FDA adverse event reports from 2005 to 2025.
Percentages show how often each reaction appears relative to total reports for pirfenidone.
These are voluntary reports and do not establish that pirfenidone caused these reactions.
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Other drugs that appear in adverse event reports alongside pirfenidone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
35.5% of pirfenidone adverse event reports involve female patients and 60.3% involve male patients. The largest age group is elderly at 85%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking pirfenidone when the adverse event was reported.
Showing 15 of 525 indications
Pirfenidone is sold under the brand name Esbriet.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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