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Piperacetazine Side Effects

The most commonly reported side effects of piperacetazine include dyspnoea, face oedema, and urticaria, based on 67 FDA adverse event reports from 2005 to 2025.

Piperacetazine side effects

Percentages show how often each reaction appears relative to total reports for piperacetazine.

1
Dyspnoea11.9%8
2
Face Oedema10.4%7
3
Urticaria10.4%7
4
Dysphonia10.4%7
5
Disorientation7.5%5
6
Confusional State7.5%5
7
Hallucination, Visual7.5%5
8
Anaemia6.0%4
9
Decreased Appetite4.5%3
10
Cardiotoxicity4.5%3
11
Hyponatraemia4.5%3
12
Rectal Haemorrhage4.5%3
13
Dehydration3.0%2
14
Seizure3.0%2
15
Thrombocytopenia3.0%2

These are voluntary reports and do not establish that piperacetazine caused these reactions.

Report severity

97.0%Serious65 reports
55.2%Hospitalizations37 reports
14.9%Fatal10 reports

Seriousness is determined by the reporter, not by OpenClaim.

Piperacetazine drug interactions

Other drugs that appear in adverse event reports alongside piperacetazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Metformin11.9%8
2
Levofloxacin7.5%5
3
Bevacizumab7.5%5
4
Aspirin6.0%4
5
Fluorouracil6.0%4
6
Dexamethasone6.0%4
7
Acetaminophen6.0%4
8
Enoxaparin-sodium6.0%4
9
Gemfibrozil6.0%4
10
Ondansetron4.5%3
11
Furosemide4.5%3
12
Tobramycin4.5%3
13
Ranibizumab3.0%2
14
Irinotecan-hydrochloride3.0%2
15
Aflibercept3.0%2

Taken alongside

1
Furosemide16.4%11
2
Allopurinol14.9%10
3
Insulin13.4%9
4
Aspirin13.4%9
5
Simvastatin11.9%8
6
Digoxin11.9%8
7
Bisoprolol-fumarate11.9%8
8
Amlodipine9.0%6
9
Doxazosin-mesylate9.0%6
10
Calcitriol6.0%4
11
Methotrexate6.0%4
12
Lansoprazole6.0%4
13
Perindopril6.0%4
14
Ramipril6.0%4
15
Verapamil-hydrochloride6.0%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports piperacetazine side effects

46.3% of piperacetazine adverse event reports involve female patients and 47.8% involve male patients. The largest age group is elderly at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female46.3%
Male47.8%
Unknown6.0%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6435.7%
65+64.3%

What is piperacetazine used for

Conditions and purposes for which patients were taking piperacetazine when the adverse event was reported.

AnaesthesiaCovid-19Chronic Obstructive Pulmonary DiseaseConstipationDiabetic RetinopathyDrug Use For Unknown IndicationHaemorrhage ProphylaxisHypertensionImmune Thrombocytopenic PurpuraProduct Used For Unknown IndicationProphylaxisProduct Used For Unknown IndicationRetinal HaemorrhageVitreous Haemorrhage

Piperacetazine brand names and reporting trend

Piperacetazine is sold under the brand name Quide.

Brand names

Quide25

Quarterly reports (20052025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking piperacetazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.