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Pipecuronium Side Effects

The most commonly reported side effects of pipecuronium include foetal exposure during pregnancy, congenital clavicular agenesis, and syndactyly, based on 51 FDA adverse event reports from 2004 to 2025.

Pipecuronium side effects

Percentages show how often each reaction appears relative to total reports for pipecuronium.

1
Foetal Exposure During Pregnancy19.6%10
2
Congenital Clavicular Agenesis15.7%8
3
Syndactyly15.7%8
4
Adrenal Insufficiency15.7%8
5
Dysmorphism15.7%8
6
Cardiac Failure13.7%7
7
Hypoglycaemia13.7%7
8
Dyspnoea11.8%6
9
Cardiac Arrest11.8%6
10
Anaemia11.8%6
11
Sinus Tachycardia11.8%6
12
Urinary Retention9.8%5
13
Hypokinesia9.8%5
14
Thyroid Cyst9.8%5
15
Ejection Fraction Decreased9.8%5

These are voluntary reports and do not establish that pipecuronium caused these reactions.

Report severity

82.4%Serious42 reports
13.7%Hospitalizations7 reports
21.6%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Pipecuronium drug interactions

Other drugs that appear in adverse event reports alongside pipecuronium. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Propofol47.1%24
2
Midazolam37.3%19
3
Sevoflurane33.3%17
4
Enoxaparin-sodium33.3%17
5
Sufentanil-citrate31.4%16
6
Heparin31.4%16
7
Isoflurane29.4%15
8
Pantoprazole-sodium29.4%15
9
Digoxin29.4%15
10
Metoprolol29.4%15
11
Pseudoephedrine29.4%15
12
Ampicillin29.4%15
13
Protamine-sulfate23.5%12
14
Epinephrine13.7%7
15
Propylthiouracil13.7%7

Taken alongside

1
Fentanyl29.4%15
2
Atropine11.8%6
3
Isoflurane11.8%6
4
Propofol11.8%6
5
Ketamine-hydrochloride9.8%5
6
Methohexital-sodium9.8%5
7
Succinylcholine-chloride9.8%5
8
Oxygen9.8%5
9
Ceftriaxone-sodium9.8%5
10
Furosemide7.8%4
11
Oxytocin7.8%4
12
Sodium-chloride7.8%4
13
Droperidol5.9%3
14
Dexamethasone5.9%3
15
Ampicillin3.9%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports pipecuronium side effects

56.9% of pipecuronium adverse event reports involve female patients and 19.6% involve male patients. The largest age group is adult at 69%. These figures reflect who reports side effects, not underlying risk.

Sex

Female56.9%
Male19.6%
Unknown23.5%

Age group

< 213.9%
2–118.3%
12–170.0%
18–6469.4%
65+8.3%

What is pipecuronium used for

Conditions and purposes for which patients were taking pipecuronium when the adverse event was reported.

AnaesthesiaAnalgesic TherapyCovid-19Endotracheal IntubationEpilepsyFoetal Exposure During PregnancyFoetal Exposure During PregnancyGeneral AnaesthesiaHypotoniaHypotoniaInduction Of AnaesthesiaInduction Of AnaesthesiaMaintenance Of AnaesthesiaMeningoencephalitis ViralMuscle Relaxant Therapy

Showing 15 of 20 indications

Pipecuronium brand names and reporting trend

Pipecuronium is sold under the brand name Arduan.

Brand names

Arduan36

Quarterly reports (20042025)

200420102025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking pipecuronium with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.