The most commonly reported side effects of pilocarpine include headache, nausea, and fatigue, based on 6,815 FDA adverse event reports from 2004 to 2025. 9.6% of reports found the drug to be ineffective.
Percentages show how often each reaction appears relative to total reports for pilocarpine.
These are voluntary reports and do not establish that pilocarpine caused these reactions.
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Other drugs that appear in adverse event reports alongside pilocarpine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
68.1% of pilocarpine adverse event reports involve female patients and 22.3% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking pilocarpine when the adverse event was reported.
Showing 15 of 197 indications
Pilocarpine is sold under brand names including Ocusert Pilo-20, Vuity.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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