OpenClaim

Phenprocoumon Side Effects

The most commonly reported side effects of phenprocoumon include general physical health deterioration, dyspnoea, and anaemia, based on 2,801 FDA adverse event reports from 2004 to 2025.

Phenprocoumon side effects

Percentages show how often each reaction appears relative to total reports for phenprocoumon.

1
General Physical Health Deterioration10.5%294
2
Dyspnoea8.7%245
3
Anaemia7.4%206
4
Dizziness6.7%189
5
Fall6.4%179
6
Drug Interaction5.0%139
7
Acute Kidney Injury4.9%137
8
Hypotension4.8%135
9
Atrial Fibrillation4.7%132
10
Nausea4.7%132
11
Haematochezia4.3%121
12
Fatigue3.9%108
13
Product Monitoring Error3.7%104
14
Product Prescribing Error3.7%103
15
Oedema Peripheral3.3%93

These are voluntary reports and do not establish that phenprocoumon caused these reactions.

Report severity

99.2%Serious2,779 reports
77.7%Hospitalizations2,175 reports
9.7%Fatal273 reports

Seriousness is determined by the reporter, not by OpenClaim.

Phenprocoumon drug interactions

Other drugs that appear in adverse event reports alongside phenprocoumon. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Metoprolol8.6%242
2
Aspirin7.8%219
3
Phentermine7.3%205
4
Ramipril6.6%185
5
Torsemide5.0%140
6
Gemfibrozil4.9%136
7
Spironolactone4.6%130
8
Prednisolone4.2%117
9
Furosemide3.8%106
10
Ibuprofen3.7%105
11
Amiodarone-hydrochloride3.6%102
12
Simvastatin3.4%95
13
Quetiapine-fumarate3.0%85
14
Allopurinol2.7%76
15
Candesartan-cilexetil2.7%75

Taken alongside

1
Pantoprazole-sodium24.1%676
2
Metoprolol19.3%540
3
Simvastatin15.5%434
4
Ramipril15.0%420
5
Bisoprolol-fumarate14.9%417
6
Phentermine12.9%361
7
Atorvastatin-calcium11.7%328
8
Allopurinol11.6%326
9
Levothyroxine-sodium8.5%239
10
Furosemide8.3%232
11
Insulin7.9%220
12
Amlodipine7.5%209
13
Digitoxin6.9%193
14
Candesartan-cilexetil6.6%184
15
Torsemide6.5%183

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports phenprocoumon side effects

43.6% of phenprocoumon adverse event reports involve female patients and 49.9% involve male patients. The largest age group is elderly at 78%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.6%
Male49.9%
Unknown6.5%

Age group

< 20.2%
2–110.2%
12–170.5%
18–6420.9%
65+78.2%

What is phenprocoumon used for

Conditions and purposes for which patients were taking phenprocoumon when the adverse event was reported.

Acute Coronary SyndromeAnticoagulant TherapyAntiphospholipid SyndromeAntiplatelet TherapyAortic Valve ProlapseAortic Valve ReplacementArrhythmiaArrhythmia ProphylaxisArterial Occlusive DiseaseArterial ThrombosisAtrial FibrillationAtrial FlutterAtrial TachycardiaAtrial ThrombosisAcute Myocardial Infarction

Showing 15 of 118 indications

Phenprocoumon brand names and reporting trend

Phenprocoumon is sold under the brand name Liquamar.

Brand names

Liquamar2,988

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking phenprocoumon with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.