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Phenmetrazine Side Effects

The most commonly reported side effects of phenmetrazine include dizziness, arthritis, and blood cholesterol increased, based on 7 FDA adverse event reports from 2005 to 2025.

Phenmetrazine side effects

Percentages show how often each reaction appears relative to total reports for phenmetrazine.

1
Dizziness28.6%2
2
Arthritis14.3%1
3
Blood Cholesterol Increased14.3%1
4
Carpal Tunnel Syndrome14.3%1
5
Depression14.3%1
6
Disorientation14.3%1
7
Fatigue14.3%1
8
Hypothyroidism14.3%1
9
Hysterectomy14.3%1
10
Intervertebral Disc Degeneration14.3%1
11
Pain14.3%1
12
Panic Disorder14.3%1
13
Sinusitis14.3%1
14
Surgery14.3%1
15
Thinking Abnormal14.3%1

These are voluntary reports and do not establish that phenmetrazine caused these reactions.

Report severity

42.9%Serious3 reports
14.3%Hospitalizations1 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Phenmetrazine drug interactions

Other drugs that appear in adverse event reports alongside phenmetrazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Interferon14.3%1
2
Esomeprazole14.3%1
3
Amitriptyline-hydrochloride14.3%1
4
Chlordiazepoxide14.3%1
5
Ethchlorvynol14.3%1
6
Amphetamine14.3%1
7
Dextroamphetamine14.3%1
8
Phentermine14.3%1
9
Diethylpropion-hydrochloride14.3%1
10
Methadone-hydrochloride14.3%1
11
Naloxone-hydrochloride14.3%1
12
Pentazocine14.3%1
13
Butalbital14.3%1
14
Triazolam14.3%1
15
Clorazepate-dipotassium14.3%1

Taken alongside

1
Ipratropium-bromide28.6%2
2
Loratadine28.6%2
3
Sucralfate28.6%2
4
Gabapentin28.6%2
5
Pantoprazole-sodium14.3%1
6
Enalaprilat14.3%1
7
Enalapril-maleate14.3%1
8
Estropipate14.3%1
9
Albuterol14.3%1
10
Fexofenadine-hydrochloride14.3%1
11
Ranitidine14.3%1
12
Montelukast-sodium14.3%1
13
Fluorometholone14.3%1
14
Lansoprazole14.3%1
15
Clorazepate-dipotassium14.3%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports phenmetrazine side effects

71.4% of phenmetrazine adverse event reports involve female patients and 14.3% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female71.4%
Male14.3%
Unknown14.3%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6440.0%
65+60.0%

What is phenmetrazine used for

Conditions and purposes for which patients were taking phenmetrazine when the adverse event was reported.

Product Used For Unknown IndicationProduct Used For Unknown Indication

Phenmetrazine brand names and reporting trend

Phenmetrazine is sold under the brand name Preludin.

Brand names

Preludin5

Quarterly reports (20052025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking phenmetrazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.