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Patiromer Side Effects

The most commonly reported side effects of patiromer include constipation, death, and diarrhoea, based on 13,658 FDA adverse event reports from 2007 to 2025. 2.5% of reports found the drug to be ineffective.

Patiromer side effects

Percentages show how often each reaction appears relative to total reports for patiromer.

1
Constipation15.7%2,140
2
Death13.1%1,794
3
Diarrhoea9.4%1,283
4
Hospitalisation7.0%961
5
Off Label Use6.6%907
6
Blood Potassium Increased5.8%795
7
Nausea5.1%698
8
Drug Dose Omission4.9%672
9
Malaise4.2%572
10
Abdominal Discomfort3.9%531
11
Inappropriate Schedule Of Drug Administration3.4%461
12
Vomiting3.3%447
13
Abdominal Pain Upper3.0%416
14
No Adverse Event2.8%377
15
Flatulence2.7%365

These are voluntary reports and do not establish that patiromer caused these reactions.

Report severity

48.6%Serious6,643 reports
27.4%Hospitalizations3,745 reports
15.3%Fatal2,089 reports

Seriousness is determined by the reporter, not by OpenClaim.

Patiromer drug interactions

Other drugs that appear in adverse event reports alongside patiromer. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Losartan-potassium0.6%83
2
Metoprolol0.6%81
3
Pantoprazole-sodium0.6%78
4
Enalapril-maleate0.6%77
5
Hydralazine-hydrochloride0.5%74
6
Hydrochlorothiazide0.5%74
7
Abatacept0.5%74
8
Ciprofloxacin0.5%73
9
Methotrexate0.5%72
10
Cephalexin0.5%71
11
Penicillin0.5%71
12
Leflunomide0.5%71
13
Hydroxychloroquine-sulfate0.5%71
14
Celecoxib0.5%71
15
Moxifloxacin-hydrochloride0.5%71

Taken alongside

1
Aspirin19.4%2,647
2
Amlodipine16.8%2,293
3
Insulin15.8%2,156
4
Furosemide14.8%2,024
5
Atorvastatin-calcium13.7%1,871
6
Ergocalciferol13.3%1,811
7
Metoprolol11.4%1,561
8
Carvedilol11.2%1,532
9
Acetaminophen9.8%1,334
10
Sodium-bicarbonate9.4%1,289
11
Levothyroxine-sodium9.4%1,283
12
Gabapentin8.2%1,118
13
Lisinopril7.9%1,081
14
Hydralazine-hydrochloride7.8%1,059
15
Omeprazole7.6%1,034

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports patiromer side effects

41.8% of patiromer adverse event reports involve female patients and 55.6% involve male patients. The largest age group is elderly at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.8%
Male55.6%
Unknown2.6%

Age group

< 2<0.1%
2–11<0.1%
12–170.2%
18–6433.0%
65+66.7%

What is patiromer used for

Conditions and purposes for which patients were taking patiromer when the adverse event was reported.

AcidosisAcute Kidney InjuryAcute Respiratory FailureAnaemiaArteriosclerosis Coronary ArteryAcute Kidney InjuryBlood PhosphorusBlood Phosphorus DecreasedBlood Phosphorus IncreasedBlood PotassiumBlood Potassium AbnormalBlood Potassium DecreasedBlood Potassium IncreasedBlood Pressure MeasurementBlood Sodium Increased

Showing 15 of 114 indications

Patiromer brand names and reporting trend

Patiromer is sold under the brand name Veltassa.

Brand names

Veltassa235

Quarterly reports (20072025)

200720202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking patiromer with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.