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Paricalcitol Side Effects

The most commonly reported side effects of paricalcitol include death, cardiac disorder, and myocardial infarction, based on 14,218 FDA adverse event reports from 2004 to 2025.

Paricalcitol side effects

Percentages show how often each reaction appears relative to total reports for paricalcitol.

1
Death24.5%3,479
2
Cardiac Disorder4.2%603
3
Myocardial Infarction3.6%515
4
Cardio-respiratory Arrest3.1%444
5
Sepsis2.9%411
6
Cardiac Failure2.0%288
7
Infarction1.8%258
8
Renal Failure1.7%245
9
Dyspnoea1.7%241
10
Cerebrovascular Accident1.7%238
11
Chronic Kidney Disease1.7%237
12
Pneumonia1.6%224
13
Respiratory Arrest1.4%200
14
Nausea1.4%197
15
Adverse Event1.4%195

These are voluntary reports and do not establish that paricalcitol caused these reactions.

Report severity

90.3%Serious12,841 reports
26.1%Hospitalizations3,717 reports
59.4%Fatal8,451 reports

Seriousness is determined by the reporter, not by OpenClaim.

Paricalcitol drug interactions

Other drugs that appear in adverse event reports alongside paricalcitol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cinacalcet-hydrochloride1.6%228
2
Esomeprazole1.4%194
3
Omeprazole1.2%165
4
Dextrose1.1%154
5
Sodium-chloride1.1%154
6
Magnesium-chloride1.0%137
7
Calcium-chloride1.0%136
8
Sodium-lactate1.0%136
9
Lenalidomide0.9%134
10
Heparin0.8%116
11
Pantoprazole-sodium0.8%112
12
Gadopentetate-dimeglumine0.8%111
13
Lansoprazole0.7%103
14
Patiromer-sorbitex-calcium0.7%102
15
Gadodiamide0.7%97

Taken alongside

1
Aspirin8.3%1,187
2
Furosemide8.1%1,152
3
Sevelamer7.4%1,051
4
Amlodipine7.2%1,029
5
Metoprolol6.4%903
6
Insulin6.0%854
7
Omeprazole5.1%721
8
Atorvastatin-calcium4.9%693
9
Carvedilol4.8%689
10
Folic-acid4.6%656
11
Levothyroxine-sodium4.5%634
12
Acetaminophen4.4%631
13
Allopurinol4.3%607
14
Losartan-potassium3.9%559
15
Clonidine3.9%556

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports paricalcitol side effects

43.0% of paricalcitol adverse event reports involve female patients and 53.8% involve male patients. The largest age group is adult at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.0%
Male53.8%
Unknown3.3%

Age group

< 20.1%
2–110.2%
12–170.5%
18–6457.2%
65+42.0%

What is paricalcitol used for

Conditions and purposes for which patients were taking paricalcitol when the adverse event was reported.

Acquired Cystic Kidney DiseaseAcute Kidney InjuryAdenocarcinoma PancreasAnaemiaAntidepressant TherapyAstheniaAzotaemiaAdenocarcinoma PancreasAnxietyBlood CalciumBlood Calcium AbnormalBlood Calcium DecreasedBlood Creatine AbnormalBlood Creatinine AbnormalBlood Creatinine Increased

Showing 15 of 154 indications

Paricalcitol brand names and reporting trend

Paricalcitol is sold under the brand name Paricalcitol.

Brand names

Paricalcitol1,136

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking paricalcitol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.