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Olaratumab Side Effects

The most commonly reported side effects of olaratumab include off label use, neutropenia, and infusion related reaction, based on 610 FDA adverse event reports from 2015 to 2025. 8.4% of reports found the drug to be ineffective.

Olaratumab side effects

Percentages show how often each reaction appears relative to total reports for olaratumab.

1
Off Label Use20.7%126
2
Neutropenia11.1%68
3
Infusion Related Reaction10.7%65
4
Febrile Neutropenia9.7%59
5
Drug Ineffective8.4%51
6
Death7.2%44
7
Malignant Neoplasm Progression7.2%44
8
Product Use In Unapproved Indication7.0%43
9
Disease Progression5.9%36
10
Anaphylactic Reaction4.8%29
11
Dyspnoea4.8%29
12
Nausea3.9%24
13
Diarrhoea3.6%22
14
Fatigue3.3%20
15
Anaemia3.3%20

These are voluntary reports and do not establish that olaratumab caused these reactions.

Report severity

87.9%Serious536 reports
29.5%Hospitalizations180 reports
19.7%Fatal120 reports

Seriousness is determined by the reporter, not by OpenClaim.

Olaratumab drug interactions

Other drugs that appear in adverse event reports alongside olaratumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Doxorubicin-hydrochloride38.0%232
2
Gemcitabine14.6%89
3
Docetaxel13.1%80
4
Pazopanib-hydrochloride10.2%62
5
Ifosfamide8.5%52
6
Trabectedin4.3%26
7
Vincristine-sulfate4.3%26
8
Topotecan-hydrochloride4.1%25
9
Paclitaxel3.6%22
10
Etoposide3.3%20
11
Mesna3.0%18
12
Carboplatin1.8%11
13
Pegfilgrastim1.6%10
14
Temozolomide1.6%10
15
Dexrazoxane-hydrochloride1.5%9

Taken alongside

1
Doxorubicin-hydrochloride20.0%122
2
Dexamethasone12.0%73
3
Diphenhydramine7.4%45
4
Ondansetron7.0%43
5
Pegfilgrastim4.3%26
6
Aprepitant4.1%25
7
Palonosetron-hydrochloride3.6%22
8
Gabapentin3.4%21
9
Prochlorperazine3.3%20
10
Acetaminophen3.3%20
11
Pantoprazole-sodium3.1%19
12
Oxycodone3.0%18
13
Fentanyl3.0%18
14
Dexrazoxane-hydrochloride2.8%17
15
Famotidine2.3%14

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports olaratumab side effects

42.0% of olaratumab adverse event reports involve female patients and 43.3% involve male patients. The largest age group is adult at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female42.0%
Male43.3%
Unknown14.8%

Age group

< 20.0%
2–111.4%
12–170.7%
18–6464.0%
65+33.8%

What is olaratumab used for

Conditions and purposes for which patients were taking olaratumab when the adverse event was reported.

Abdominal NeoplasmAnaplastic AstrocytomaAngiosarcomaAngiosarcoma MetastaticAngiosarcoma RecurrentAstrocytomaAdenocarcinoma PancreasBladder CancerBreast Cancer MetastaticBreast SarcomaBone Marrow InfiltrationCardiac Neoplasm MalignantChemotherapyChloromaColon Cancer Metastatic

Showing 15 of 99 indications

Olaratumab brand names and reporting trend

Olaratumab is sold under the brand name Lartruvo.

Brand names

Lartruvo376

Quarterly reports (20152025)

2015202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking olaratumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.