OpenClaim

Octreotide Side Effects

The most commonly reported side effects of octreotide include diarrhoea, death, and fatigue, based on 34,901 FDA adverse event reports from 2004 to 2025. 5.6% of reports found the drug to be ineffective.

Octreotide side effects

Percentages show how often each reaction appears relative to total reports for octreotide.

1
Diarrhoea13.5%4,706
2
Death13.2%4,607
3
Fatigue10.5%3,680
4
Malaise9.0%3,152
5
Blood Pressure Increased8.8%3,087
6
Nausea8.8%3,062
7
Needle Issue7.9%2,771
8
Pain7.8%2,706
9
Malignant Neoplasm Progression7.5%2,606
10
Abdominal Pain7.3%2,546
11
Blood Pressure Systolic Increased7.0%2,457
12
Asthenia7.0%2,431
13
Weight Decreased6.8%2,389
14
Injection Site Pain6.6%2,310
15
Headache6.1%2,132

These are voluntary reports and do not establish that octreotide caused these reactions.

Report severity

79.2%Serious27,628 reports
34.4%Hospitalizations12,022 reports
22.1%Fatal7,704 reports

Seriousness is determined by the reporter, not by OpenClaim.

Octreotide drug interactions

Other drugs that appear in adverse event reports alongside octreotide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Everolimus5.9%2,063
2
Metformin1.6%568
3
Telotristat-etiprate1.5%508
4
Pegvisomant1.4%490
5
Amlodipine1.3%444
6
Pantoprazole-sodium1.3%441
7
Capecitabine1.1%397
8
Sunitinib-malate1.0%352
9
Metoprolol0.9%328
10
Lanreotide-acetate0.9%319
11
Lutetium0.9%306
12
Atorvastatin-calcium0.8%271
13
Ramipril0.7%243
14
Bevacizumab0.7%234
15
Apomorphine-hydrochloride0.7%227

Taken alongside

1
Levothyroxine-sodium5.0%1,760
2
Acetaminophen4.5%1,570
3
Aspirin3.6%1,253
4
Amlodipine3.5%1,228
5
Furosemide3.5%1,225
6
Ergocalciferol3.5%1,218
7
Pantoprazole-sodium3.3%1,144
8
Metformin3.2%1,109
9
Omeprazole3.0%1,049
10
Hydrochlorothiazide2.9%1,012
11
Insulin2.7%951
12
Atorvastatin-calcium2.7%931
13
Loperamide-hydrochloride2.7%927
14
Ondansetron2.5%858
15
Metoprolol2.2%775

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports octreotide side effects

48.1% of octreotide adverse event reports involve female patients and 40.6% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female48.1%
Male40.6%
Unknown11.3%

Age group

< 22.0%
2–110.8%
12–170.6%
18–6450.3%
65+46.3%

What is octreotide used for

Conditions and purposes for which patients were taking octreotide when the adverse event was reported.

5-hydroxyindolacetic Acid In Urine IncreasedAbdominal DiscomfortAbdominal DistensionAbdominal NeoplasmAbdominal PainAbnormal FaecesAcral OvergrowthAcromegalyActh-producing Pituitary TumourAcute Graft Versus Host DiseaseAcute Graft Versus Host Disease In IntestineAcute Kidney InjuryAcute Lymphocytic LeukaemiaAdenocarcinomaAdenocarcinoma Gastric

Showing 15 of 1,216 indications

Octreotide brand names and reporting trend

Octreotide is sold under the brand name Mycapssa.

Brand names

Mycapssa10,355

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking octreotide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.