OpenClaim

Ocriplasmin Side Effects

The most commonly reported side effects of ocriplasmin include visual acuity reduced, photopsia, and visual impairment, based on 695 FDA adverse event reports from 2012 to 2022.

Ocriplasmin side effects

Percentages show how often each reaction appears relative to total reports for ocriplasmin.

1
Visual Acuity Reduced29.5%205
2
Photopsia23.0%160
3
Visual Impairment20.1%140
4
No Therapeutic Response16.8%117
5
Vitreous Floaters15.1%105
6
Vision Blurred14.7%102
7
Macular Hole10.9%76
8
Retinal Injury10.8%75
9
Chromatopsia9.6%67
10
Retinal Detachment9.6%67
11
Eye Pain8.8%61
12
Subretinal Fluid7.6%53
13
Metamorphopsia7.2%50
14
Photophobia7.2%50
15
Pupillary Reflex Impaired6.8%47

These are voluntary reports and do not establish that ocriplasmin caused these reactions.

Report severity

57.4%Serious399 reports
2.2%Hospitalizations15 reports
0.6%Fatal4 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ocriplasmin drug interactions

Other drugs that appear in adverse event reports alongside ocriplasmin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bevacizumab0.3%2
2
Dexamethasone0.3%2
3
Prednisolone0.3%2
4
Sodium-chloride0.1%1
5
Alteplase0.1%1
6
Dorzolamide-hydrochloride0.1%1
7
Nepafenac0.1%1
8
Ranibizumab0.1%1
9
Aflibercept0.1%1
10
Fluocinolone-acetonide0.1%1
11
Methylprednisolone0.1%1
12
Tacrolimus0.1%1
13
Cyclophosphamide0.1%1
14
Ketorolac-tromethamine0.1%1
15
Triamcinolone0.1%1

Taken alongside

1
Aspirin3.2%22
2
Omeprazole1.9%13
3
Levothyroxine-sodium1.7%12
4
Simvastatin1.6%11
5
Atorvastatin-calcium1.6%11
6
Ergocalciferol1.4%10
7
Amlodipine1.4%10
8
Metoprolol1.2%8
9
Brimonidine-tartrate1.0%7
10
Fluticasone1.0%7
11
Timolol1.0%7
12
Ramipril1.0%7
13
Hydrochlorothiazide0.9%6
14
Calcium0.9%6
15
Metformin0.9%6

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ocriplasmin side effects

37.0% of ocriplasmin adverse event reports involve female patients and 12.5% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female37.0%
Male12.5%
Unknown50.5%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6440.2%
65+59.8%

What is ocriplasmin used for

Conditions and purposes for which patients were taking ocriplasmin when the adverse event was reported.

Age-related Macular DegenerationCystoid Macular OedemaDermatomyositisEye DisorderEye DisorderGlaucomaIris AdhesionsInterstitial Lung DiseaseMacular FibrosisMacular HoleMaculopathyProduct Used For Unknown IndicationRetinal DetachmentRetinal OedemaRetinoschisis

Showing 15 of 19 indications

Ocriplasmin brand names and reporting trend

Ocriplasmin is sold under the brand name Jetrea.

Brand names

Jetrea9

Quarterly reports (20122022)

2012201620202022

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ocriplasmin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.