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Nizatidine Side Effects

The most commonly reported side effects of nizatidine include chronic kidney disease, acute kidney injury, and renal failure, based on 5,466 FDA adverse event reports from 2004 to 2025.

Nizatidine side effects

Percentages show how often each reaction appears relative to total reports for nizatidine.

1
Chronic Kidney Disease9.2%503
2
Acute Kidney Injury7.5%408
3
Renal Failure4.9%268
4
Nausea4.4%240
5
Vomiting3.7%201
6
Malaise3.4%187
7
Dyspnoea3.3%183
8
Confusional State3.3%180
9
Headache3.1%167
10
Dizziness3.1%167
11
Fatigue2.9%160
12
Diarrhoea2.7%149
13
Abdominal Pain2.6%141
14
Gastrooesophageal Reflux Disease2.5%138
15
Hyponatraemia2.5%136

These are voluntary reports and do not establish that nizatidine caused these reactions.

Report severity

89.3%Serious4,881 reports
40.5%Hospitalizations2,214 reports
9.5%Fatal520 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nizatidine drug interactions

Other drugs that appear in adverse event reports alongside nizatidine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Omeprazole11.2%613
2
Esomeprazole9.5%518
3
Lansoprazole9.1%496
4
Pantoprazole-sodium7.6%418
5
Dexlansoprazole3.6%195
6
Adalimumab2.0%112
7
Gabapentin2.0%112
8
Dexamethasone1.9%106
9
Clozapine1.9%103
10
Amlodipine1.7%94
11
Donepezil-hydrochloride1.6%87
12
Lenalidomide1.5%82
13
Atorvastatin-calcium1.5%80
14
Trastuzumab1.5%80
15
Sertraline-hydrochloride1.4%78

Taken alongside

1
Acetaminophen31.7%1,731
2
Omeprazole18.0%985
3
Aspirin17.2%939
4
Atorvastatin-calcium15.5%849
5
Albuterol14.4%788
6
Furosemide13.6%744
7
Ranitidine13.0%708
8
Lansoprazole12.8%700
9
Amlodipine12.4%676
10
Levothyroxine-sodium10.2%558
11
Simvastatin10.0%544
12
Famotidine9.3%508
13
Ibuprofen9.0%491
14
Metformin8.1%445
15
Gabapentin8.1%444

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nizatidine side effects

54.3% of nizatidine adverse event reports involve female patients and 37.5% involve male patients. The largest age group is elderly at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female54.3%
Male37.5%
Unknown8.2%

Age group

< 20.5%
2–110.9%
12–171.1%
18–6443.5%
65+54.0%

What is nizatidine used for

Conditions and purposes for which patients were taking nizatidine when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAdverse EventAllergy To ChemicalsAnal FissureAntacid TherapyAntiallergic TherapyAnxietyAnxiety DisorderAsthmaAutoimmune DisorderAdverse Drug ReactionAnaphylactic ReactionAntiallergic Therapy

Showing 15 of 159 indications

Nizatidine brand names and reporting trend

Nizatidine is sold under the brand name Nizatidine.

Brand names

Nizatidine1,617

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nizatidine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.