OpenClaim

Nitric Side Effects

The most commonly reported side effects of nitric include no adverse event, device malfunction, and device issue, based on 4,387 FDA adverse event reports from 2004 to 2025. 6.9% of reports found the drug to be ineffective.

Nitric side effects

Percentages show how often each reaction appears relative to total reports for nitric.

1
No Adverse Event18.0%789
2
Device Malfunction12.9%567
3
Device Issue9.9%434
4
Underdose9.5%417
5
Death8.2%359
6
Product Use Issue7.8%340
7
Off Label Use7.6%332
8
Drug Ineffective6.9%301
9
Oxygen Saturation Decreased4.5%199
10
Product Use In Unapproved Indication4.5%197
11
Condition Aggravated3.9%171
12
Respiratory Failure2.8%125
13
Pulmonary Hypertension2.8%122
14
Device Delivery System Issue2.8%122
15
Hypoxia2.7%119

These are voluntary reports and do not establish that nitric caused these reactions.

Report severity

64.6%Serious2,836 reports
17.3%Hospitalizations759 reports
28.9%Fatal1,267 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nitric drug interactions

Other drugs that appear in adverse event reports alongside nitric. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sildenafil-citrate5.5%243
2
Epinephrine3.9%171
3
Epoprostenol-sodium3.7%163
4
Bosentan3.6%159
5
Treprostinil3.2%142
6
Dexamethasone2.9%128
7
Azithromycin2.6%114
8
Milrinone-lactate2.4%105
9
Vancomycin2.4%104
10
Propofol2.3%100
11
Fentanyl2.1%92
12
Midazolam2.1%91
13
Remdesivir2.1%90
14
Hydrocortisone1.9%84
15
Heparin1.9%84

Taken alongside

1
Epinephrine6.2%273
2
Sildenafil-citrate4.7%208
3
Milrinone-lactate4.2%186
4
Dobutamine-hydrochloride3.9%172
5
Dopamine-hydrochloride3.9%171
6
Oxygen3.7%164
7
Furosemide3.6%158
8
Fentanyl3.1%136
9
Vasopressin2.7%118
10
Vancomycin2.3%102
11
Midazolam2.2%97
12
Ampicillin2.1%93
13
Epoprostenol-sodium2.1%91
14
Heparin1.9%84
15
Gentamicin-sulfate1.7%76

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nitric side effects

25.3% of nitric adverse event reports involve female patients and 27.7% involve male patients. The largest age group is adult at 35%. These figures reflect who reports side effects, not underlying risk.

Sex

Female25.3%
Male27.7%
Unknown47.0%

Age group

< 240.4%
2–115.8%
12–174.0%
18–6435.2%
65+14.5%

What is nitric used for

Conditions and purposes for which patients were taking nitric when the adverse event was reported.

Accidental ExposureAcute Myocardial InfarctionAcute Respiratory Distress SyndromeAcute Respiratory FailureAcute Right Ventricular FailureAdverse EventAlveolar Capillary DysplasiaAnaesthesiaAnaesthesia ProcedureAortic AneurysmAsthmaAtopyAtrial Septal DefectAcidosisAcute Graft Versus Host Disease

Showing 15 of 333 indications

Nitric brand names and reporting trend

Nitric is sold under the brand name Inomax.

Brand names

Inomax2,545

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nitric with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.