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Nisoldipine Side Effects

The most commonly reported side effects of nisoldipine include dizziness, nausea, and asthenia, based on 1,261 FDA adverse event reports from 2004 to 2025. 4.7% of reports found the drug to be ineffective.

Nisoldipine side effects

Percentages show how often each reaction appears relative to total reports for nisoldipine.

1
Drug Ineffective4.7%59
2
Dizziness4.6%58
3
Nausea4.6%58
4
Asthenia3.8%48
5
Headache3.8%48
6
Oedema Peripheral3.7%47
7
Chronic Kidney Disease3.6%46
8
Renal Failure3.6%45
9
Fatigue3.4%43
10
Myocardial Infarction3.3%41
11
Dyspnoea3.2%40
12
Pain3.1%39
13
Fatigue2.9%36
14
Diarrhoea2.8%35
15
Pruritus2.7%34

These are voluntary reports and do not establish that nisoldipine caused these reactions.

Report severity

65.0%Serious820 reports
32.4%Hospitalizations409 reports
10.2%Fatal129 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nisoldipine drug interactions

Other drugs that appear in adverse event reports alongside nisoldipine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Esomeprazole3.9%49
2
Adalimumab3.7%47
3
Amlodipine3.6%46
4
Rosiglitazone-maleate3.1%39
5
Lenalidomide3.1%39
6
Omeprazole3.0%38
7
Varenicline1.9%24
8
Sodium-oxybate1.9%24
9
Simvastatin1.7%22
10
Rofecoxib1.7%22
11
Furosemide1.7%22
12
Pantoprazole-sodium1.7%21
13
Hydrochlorothiazide1.6%20
14
Teriparatide1.5%19
15
Atorvastatin-calcium1.5%19

Taken alongside

1
Aspirin24.4%308
2
Hydrochlorothiazide18.6%235
3
Metoprolol18.5%233
4
Acetaminophen17.3%218
5
Furosemide15.7%198
6
Lisinopril13.2%166
7
Simvastatin13.0%164
8
Levothyroxine-sodium12.5%157
9
Metformin10.4%131
10
Atorvastatin-calcium9.5%120
11
Ergocalciferol9.4%119
12
Losartan-potassium9.3%117
13
Albuterol9.0%113
14
Atenolol8.4%106
15
Hydrocodone8.3%105

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nisoldipine side effects

60.1% of nisoldipine adverse event reports involve female patients and 37.4% involve male patients. The largest age group is elderly at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.1%
Male37.4%
Unknown2.5%

Age group

< 20.0%
2–110.0%
12–170.1%
18–6443.2%
65+56.7%

What is nisoldipine used for

Conditions and purposes for which patients were taking nisoldipine when the adverse event was reported.

Angina PectorisBlood PressureBlood Pressure AbnormalBlood Pressure IncreasedBlood Pressure MeasurementBlood Pressure AbnormalBlood Pressure IncreasedBlood Pressure MeasurementCardiac DisorderCardiomyopathyCardiovascular DisorderChest PainCompleted SuicideCoronary Artery DiseaseCardiac Failure

Showing 15 of 41 indications

Nisoldipine brand names and reporting trend

Nisoldipine is sold under the brand name Sular.

Brand names

Sular474

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nisoldipine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.