The most commonly reported side effects of nirmatrelvir include covid-19, disease recurrence, and dysgeusia, based on 53,393 FDA adverse event reports from 2010 to 2025.
Percentages show how often each reaction appears relative to total reports for nirmatrelvir.
These are voluntary reports and do not establish that nirmatrelvir caused these reactions.
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Other drugs that appear in adverse event reports alongside nirmatrelvir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
58.0% of nirmatrelvir adverse event reports involve female patients and 31.8% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking nirmatrelvir when the adverse event was reported.
Showing 15 of 147 indications
Nirmatrelvir is sold under the brand name Paxlovid (copackaged).
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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