OpenClaim

Nifurtimox Side Effects

The most commonly reported side effects of nifurtimox include nausea, asthenia, and dysmetria, based on 79 FDA adverse event reports from 2004 to 2023.

#1 Reported: NauseaAll side effects ↓Top Co-Medication: Eflornithine-hydrochlorideDrug interactions ↓64% of Reports Are AdultDemographics ↓

Nifurtimox side effects

Percentages show how often each reaction appears relative to total reports for nifurtimox.

1
Nausea11.4%9
2
Asthenia10.1%8
3
Dysmetria10.1%8
4
Vision Blurred10.1%8
5
Vomiting8.9%7
6
Neuroblastoma8.9%7
7
Convulsion7.6%6
8
Pyrexia6.3%5
9
Malignant Neoplasm Progression6.3%5
10
Neutropenia5.1%4
11
Pancytopenia3.8%3
12
Condition Aggravated3.8%3
13
Headache3.8%3
14
Liver Disorder3.8%3
15
Pleural Effusion3.8%3

These are voluntary reports and do not establish that nifurtimox caused these reactions.

Report severity

91.1%Serious72 reports
38.0%Hospitalizations30 reports
19.0%Fatal15 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nifurtimox drug interactions

Other drugs that appear in adverse event reports alongside nifurtimox. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Eflornithine-hydrochloride8.9%7
2
Pravastatin-sodium8.9%7
3
Levetiracetam7.6%6
4
Cyclophosphamide7.6%6
5
Topotecan-hydrochloride6.3%5
6
Lacosamide3.8%3
7
Prednisolone3.8%3
8
Doxycycline2.5%2
9
Amoxicillin2.5%2
10
Clavulanate-potassium2.5%2
11
Ciprofloxacin2.5%2
12
Acetaminophen1.3%1
13
Omeprazole1.3%1
14
Doxepin-hydrochloride1.3%1
15
Deferoxamine-mesylate1.3%1

Taken alongside

1
Prednisone11.4%9
2
Ondansetron10.1%8
3
Acetaminophen10.1%8
4
Levetiracetam7.6%6
5
Lorazepam6.3%5
6
Diphenhydramine6.3%5
7
Apomorphine-hydrochloride6.3%5
8
Gabapentin5.1%4
9
Polyethylene-glycol-33505.1%4
10
Insulin3.8%3
11
Oxycodone3.8%3
12
Oxcarbazepine3.8%3
13
Hydromorphone-hydrochloride3.8%3
14
Furosemide3.8%3
15
Dexamethasone3.8%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nifurtimox side effects

44.3% of nifurtimox adverse event reports involve female patients and 48.1% involve male patients. The largest age group is adult at 64%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.3%
Male48.1%
Unknown7.6%

Age group

< 21.8%
2–1123.2%
12–175.4%
18–6464.3%
65+5.4%

What is nifurtimox used for

Conditions and purposes for which patients were taking nifurtimox when the adverse event was reported.

African TrypanosomiasisAmerican TrypanosomiasisAfrican TrypanosomiasisAmerican TrypanosomiasisComplex Partial SeizuresConvulsionDrug Use For Unknown IndicationEpilepsyGeneralised Tonic-clonic SeizureGrand Mal ConvulsionMedulloblastomaMetastatic NeoplasmNeuroblastomaNeuroblastoma RecurrentOff Label Use

Showing 15 of 22 indications

Nifurtimox brand names and reporting trend

Nifurtimox is sold under the brand name Lampit.

Brand names

Lampit88

Quarterly reports (2004–2023)

20042010201520202023

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nifurtimox with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

Check my medications