OpenClaim

Neomycin Side Effects

The most commonly reported side effects of neomycin include drug hypersensitivity, pain, and rash, based on 7,325 FDA adverse event reports from 2004 to 2025. 11.7% of reports found the drug to be ineffective.

Neomycin side effects

Percentages show how often each reaction appears relative to total reports for neomycin.

1
Drug Hypersensitivity17.4%1,275
2
Drug Ineffective11.7%859
3
Pain10.8%790
4
Rash10.7%785
5
Off Label Use10.7%781
6
Malaise9.8%718
7
Fatigue9.8%715
8
Infusion Related Reaction9.7%709
9
Vomiting9.2%676
10
Pyrexia8.9%652
11
Swelling8.9%649
12
Type 2 Diabetes Mellitus8.7%640
13
Dyspnoea8.5%624
14
Nausea8.5%623
15
Pruritus8.3%609

These are voluntary reports and do not establish that neomycin caused these reactions.

Report severity

64.7%Serious4,742 reports
31.4%Hospitalizations2,301 reports
17.1%Fatal1,252 reports

Seriousness is determined by the reporter, not by OpenClaim.

Neomycin drug interactions

Other drugs that appear in adverse event reports alongside neomycin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Polymyxin-b-sulfate30.2%2,213
2
Gramicidin17.8%1,301
3
Prednisone17.4%1,271
4
Acetaminophen16.0%1,169
5
Hydrocortisone15.5%1,135
6
Adalimumab15.4%1,127
7
Cetirizine-hydrochloride14.4%1,053
8
Abatacept13.1%961
9
Rituximab12.9%944
10
Pregabalin12.3%902
11
Methotrexate12.3%899
12
Sulfamethoxazole12.1%885
13
Pseudoephedrine11.9%871
14
Diclofenac11.8%866
15
Etanercept11.5%842

Taken alongside

1
Polymyxin-b-sulfate27.8%2,040
2
Acetaminophen20.1%1,475
3
Dexamethasone15.1%1,105
4
Ergocalciferol13.3%976
5
Hydrocortisone12.0%877
6
Levothyroxine-sodium10.5%769
7
Aspirin10.2%748
8
Lisinopril10.2%747
9
Gramicidin10.0%734
10
Ibuprofen9.8%719
11
Pantoprazole-sodium9.4%690
12
Prednisone8.8%641
13
Albuterol8.7%639
14
Furosemide8.5%620
15
Oxycodone7.6%555

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports neomycin side effects

64.4% of neomycin adverse event reports involve female patients and 24.7% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female64.4%
Male24.7%
Unknown11.0%

Age group

< 20.6%
2–112.1%
12–171.4%
18–6458.8%
65+37.0%

What is neomycin used for

Conditions and purposes for which patients were taking neomycin when the adverse event was reported.

Abdominal DistensionAbnormal Sensation In EyeAbrasionsAbscessAcanthamoeba KeratitisAccidental ExposureAccidental Exposure To ProductAccidental Exposure To Product By ChildAcneAdverse EventAdverse ReactionAmblyopiaAmmonia AbnormalAmmonia IncreasedAnalgesic Effect

Showing 15 of 485 indications

Neomycin brand names and reporting trend

Neomycin is sold under the brand name Neomycin Sulfate.

Brand names

Neomycin Sulfate3,798

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking neomycin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.