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Nelfinavir Side Effects

The most commonly reported side effects of nelfinavir include drug exposure during pregnancy, foetal exposure during pregnancy, and pain, based on 3,383 FDA adverse event reports from 2004 to 2025.

Nelfinavir side effects

Percentages show how often each reaction appears relative to total reports for nelfinavir.

1
Drug Exposure During Pregnancy14.9%503
2
Foetal Exposure During Pregnancy9.3%314
3
Pain7.2%243
4
Emotional Distress7.1%239
5
Anxiety6.9%232
6
Anhedonia6.4%217
7
Chronic Kidney Disease4.3%146
8
Drug Resistance4.0%136
9
Osteoporosis3.8%130
10
Virologic Failure3.6%123
11
Viral Mutation Identified3.4%116
12
Bone Density Decreased3.4%116
13
Pathogen Resistance3.3%111
14
Depression3.0%102
15
Lipodystrophy Acquired3.0%100

These are voluntary reports and do not establish that nelfinavir caused these reactions.

Report severity

93.5%Serious3,163 reports
25.6%Hospitalizations867 reports
7.1%Fatal241 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nelfinavir drug interactions

Other drugs that appear in adverse event reports alongside nelfinavir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lamivudine61.1%2,068
2
Zidovudine53.6%1,812
3
Stavudine31.5%1,065
4
Tenofovir28.2%954
5
Didanosine26.0%880
6
Ritonavir25.2%851
7
Efavirenz24.8%839
8
Nevirapine19.5%659
9
Lopinavir17.2%581
10
Abacavir16.4%555
11
Emtricitabine16.1%544
12
Saquinavir12.6%427
13
Indinavir-sulfate11.4%387
14
Atazanavir-sulfate7.1%239
15
Darunavir6.6%223

Taken alongside

1
Lamivudine17.4%588
2
Zidovudine13.9%469
3
Ritonavir10.4%351
4
Tenofovir9.9%336
5
Stavudine7.9%268
6
Abacavir7.8%265
7
Emtricitabine7.6%257
8
Sulfamethoxazole6.1%207
9
Efavirenz6.1%205
10
Didanosine5.9%198
11
Lopinavir4.9%167
12
Trimethoprim4.9%166
13
Dolutegravir4.8%161
14
Nevirapine4.5%151
15
Atazanavir-sulfate4.0%135

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nelfinavir side effects

34.7% of nelfinavir adverse event reports involve female patients and 48.9% involve male patients. The largest age group is adult at 79%. These figures reflect who reports side effects, not underlying risk.

Sex

Female34.7%
Male48.9%
Unknown16.4%

Age group

< 212.3%
2–113.7%
12–171.4%
18–6479.3%
65+3.3%

What is nelfinavir used for

Conditions and purposes for which patients were taking nelfinavir when the adverse event was reported.

Accidental ExposureAccidental Exposure To ProductAccidental Needle StickAcquired Immunodeficiency SyndromeAcute Hiv InfectionAdenocarcinoma PancreasAntiretroviral TherapyAntiviral ProphylaxisAntiviral TreatmentAsymptomatic Hiv InfectionAntiretroviral TherapyCentral Nervous System LymphomaCervix CarcinomaChronic Hepatitis CCytomegalovirus Infection

Showing 15 of 74 indications

Nelfinavir brand names and reporting trend

Nelfinavir is sold under the brand name Viracept.

Brand names

Viracept1,832

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nelfinavir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.