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Nebivolol Side Effects

The most commonly reported side effects of nebivolol include diarrhoea, fatigue, and dyspnoea, based on 34,933 FDA adverse event reports from 2004 to 2025. 4.3% of reports found the drug to be ineffective.

Nebivolol side effects

Percentages show how often each reaction appears relative to total reports for nebivolol.

1
Diarrhoea4.8%1,676
2
Fatigue4.8%1,663
3
Dyspnoea4.4%1,550
4
Drug Ineffective4.3%1,506
5
Nausea4.2%1,484
6
Acute Kidney Injury3.8%1,311
7
Off Label Use3.6%1,260
8
Headache3.6%1,251
9
Dizziness3.5%1,213
10
Asthenia2.9%1,014
11
Fall2.9%998
12
Hypotension2.7%936
13
Hypertension2.4%852
14
Malaise2.4%840
15
Anaemia2.4%836

These are voluntary reports and do not establish that nebivolol caused these reactions.

Report severity

71.8%Serious25,098 reports
40.2%Hospitalizations14,028 reports
7.2%Fatal2,504 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nebivolol drug interactions

Other drugs that appear in adverse event reports alongside nebivolol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Metformin3.1%1,072
2
Amlodipine3.1%1,070
3
Furosemide2.9%999
4
Lenalidomide2.8%991
5
Hydrochlorothiazide2.7%949
6
Adalimumab2.7%946
7
Valsartan2.7%935
8
Pantoprazole-sodium2.5%874
9
Aspirin2.4%839
10
Omeprazole2.3%816
11
Rivaroxaban2.2%765
12
Atorvastatin-calcium2.2%755
13
Sodium-oxybate2.0%686
14
Apixaban1.8%623
15
Ramipril1.7%593

Taken alongside

1
Aspirin19.0%6,640
2
Amlodipine13.8%4,829
3
Atorvastatin-calcium13.0%4,526
4
Levothyroxine-sodium12.2%4,272
5
Furosemide11.8%4,120
6
Acetaminophen10.4%3,644
7
Omeprazole9.8%3,424
8
Ergocalciferol9.8%3,407
9
Metformin9.5%3,305
10
Pantoprazole-sodium9.4%3,273
11
Hydrochlorothiazide8.9%3,107
12
Rosuvastatin7.1%2,472
13
Simvastatin6.5%2,276
14
Allopurinol6.4%2,226
15
Insulin6.3%2,211

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nebivolol side effects

51.9% of nebivolol adverse event reports involve female patients and 41.5% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female51.9%
Male41.5%
Unknown6.5%

Age group

< 20.2%
2–11<0.1%
12–170.1%
18–6439.5%
65+60.1%

What is nebivolol used for

Conditions and purposes for which patients were taking nebivolol when the adverse event was reported.

Accelerated HypertensionAccidental ExposureAccidental Exposure To Product By ChildAcute Coronary SyndromeAcute Myocardial InfarctionAcute Pulmonary OedemaAdjuvant TherapyAdrenal DisorderAgranulocytosisAngina PectorisAngina UnstableAngioplastyAnticoagulant TherapyAnxietyAnxiety Disorder

Showing 15 of 394 indications

Nebivolol brand names and reporting trend

Nebivolol is sold under the brand name Vyduo.

Brand names

Vyduo60

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nebivolol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.