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Naxitamab Side Effects

The most commonly reported side effects of naxitamab include hypotension, pain, and hypertension, based on 236 FDA adverse event reports from 2011 to 2025.

Naxitamab side effects

Percentages show how often each reaction appears relative to total reports for naxitamab.

1
Hypotension26.7%63
2
Pain25.8%61
3
Hypertension14.0%33
4
Urticaria12.3%29
5
Off Label Use11.0%26
6
Rash10.6%25
7
Pyrexia8.1%19
8
Oxygen Saturation Decreased7.2%17
9
Bronchospasm6.4%15
10
Hypoxia6.4%15
11
Tachycardia5.9%14
12
Abdominal Pain5.5%13
13
Vomiting5.5%13
14
Anaphylactic Reaction4.7%11
15
Cough4.7%11

These are voluntary reports and do not establish that naxitamab caused these reactions.

Report severity

75.8%Serious179 reports
35.2%Hospitalizations83 reports
5.1%Fatal12 reports

Seriousness is determined by the reporter, not by OpenClaim.

Naxitamab drug interactions

Other drugs that appear in adverse event reports alongside naxitamab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Temozolomide8.5%20
2
Dinutuximab7.6%18
3
Cyclophosphamide7.6%18
4
Irinotecan-hydrochloride7.6%18
5
Topotecan-hydrochloride7.2%17
6
Sargramostim6.8%16
7
Etoposide5.5%13
8
Vincristine-sulfate5.1%12
9
Carboplatin4.2%10
10
Doxorubicin-hydrochloride4.2%10
11
Lorlatinib3.8%9
12
Thiotepa3.4%8
13
Cisplatin3.0%7
14
Ifosfamide2.5%6
15
Melphalan2.1%5

Taken alongside

1
Acetaminophen19.5%46
2
Irinotecan-hydrochloride18.2%43
3
Diphenhydramine17.8%42
4
Oxycodone16.5%39
5
Methylprednisolone16.5%39
6
Gabapentin16.1%38
7
Temozolomide15.7%37
8
Sargramostim14.4%34
9
Ondansetron12.7%30
10
Famotidine12.7%30
11
Sodium-chloride12.3%29
12
Ketamine-hydrochloride10.2%24
13
Hydromorphone-hydrochloride8.9%21
14
Cetirizine-hydrochloride8.1%19
15
Epinephrine6.8%16

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports naxitamab side effects

28.8% of naxitamab adverse event reports involve female patients and 28.4% involve male patients. The largest age group is child at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female28.8%
Male28.4%
Unknown42.8%

Age group

< 29.6%
2–1158.7%
12–1721.2%
18–646.7%
65+3.8%

What is naxitamab used for

Conditions and purposes for which patients were taking naxitamab when the adverse event was reported.

Congenital RetinoblastomaDepressionGanglioneuroblastomaImmunochemotherapyImmunomodulatory TherapyNeuroblastomaNeuroblastoma RecurrentNeuroblastomaNeuroblastoma RecurrentOsteosarcoma RecurrentProduct Used For Unknown IndicationProduct Used For Unknown IndicationRetinoblastomaSpinal Cord InjurySalvage Therapy

Naxitamab brand names and reporting trend

Naxitamab is sold under the brand name Danyelza.

Brand names

Danyelza148

Quarterly reports (20112025)

201120242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking naxitamab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.