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Nalidixic Side Effects

The most commonly reported side effects of nalidixic include pathogen resistance, drug hypersensitivity, and sepsis, based on 50 FDA adverse event reports from 2004 to 2023. 6.0% of reports found the drug to be ineffective.

Nalidixic side effects

Percentages show how often each reaction appears relative to total reports for nalidixic.

1
Pathogen Resistance20.0%10
2
Drug Hypersensitivity14.0%7
3
Sepsis10.0%5
4
Drug Resistance8.0%4
5
Anaemia6.0%3
6
Urinary Tract Infection6.0%3
7
Pyrexia6.0%3
8
Diarrhoea6.0%3
9
Drug Ineffective6.0%3
10
Depressed Level Of Consciousness6.0%3
11
Cardiac Arrest6.0%3
12
Tendon Rupture4.0%2
13
Erythema4.0%2
14
Fatigue4.0%2
15
Somnolence4.0%2

These are voluntary reports and do not establish that nalidixic caused these reactions.

Report severity

82.0%Serious41 reports
42.0%Hospitalizations21 reports
14.0%Fatal7 reports

Seriousness is determined by the reporter, not by OpenClaim.

Nalidixic drug interactions

Other drugs that appear in adverse event reports alongside nalidixic. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ampicillin30.0%15
2
Ciprofloxacin28.0%14
3
Nitrofurantoin16.0%8
4
Gentamicin-sulfate16.0%8
5
Tetracycline16.0%8
6
Meropenem14.0%7
7
Sulfisoxazole10.0%5
8
Streptomycin-sulfate10.0%5
9
Ceftazidime10.0%5
10
Cefotaxime-sodium10.0%5
11
Imipenem10.0%5
12
Adalimumab8.0%4
13
Colistin-sulfate8.0%4
14
Amoxicillin6.0%3
15
Sulfamethoxazole6.0%3

Taken alongside

1
Omeprazole8.0%4
2
Furosemide8.0%4
3
Amlodipine8.0%4
4
Insulin8.0%4
5
Nitroglycerin6.0%3
6
Gentamicin-sulfate6.0%3
7
Nitrofurantoin6.0%3
8
Sodium-chloride6.0%3
9
Tramadol-hydrochloride4.0%2
10
Sulfasalazine4.0%2
11
Hydrochlorothiazide4.0%2
12
Prednisone4.0%2
13
Losartan-potassium4.0%2
14
Phenazopyridine-hydrochloride4.0%2
15
Levothyroxine-sodium4.0%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports nalidixic side effects

60.0% of nalidixic adverse event reports involve female patients and 28.0% involve male patients. The largest age group is adult at 43%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.0%
Male28.0%
Unknown12.0%

Age group

< 212.5%
2–1112.5%
12–172.5%
18–6442.5%
65+30.0%

What is nalidixic used for

Conditions and purposes for which patients were taking nalidixic when the adverse event was reported.

CystitisDiarrhoeaGastroenteritisInfection ProphylaxisKlebsiella InfectionNasopharyngitisPneumonia KlebsiellaPolycystic OvariesProduct Used For Unknown IndicationProstatitisProteus InfectionProvidencia InfectionProduct Used For Unknown IndicationShigella InfectionUrethritis

Showing 15 of 16 indications

Nalidixic brand names and reporting trend

Nalidixic is sold under the brand name Neggram.

Brand names

Neggram50

Quarterly reports (20042023)

2004201020202023

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking nalidixic with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.