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Moxifloxacin Side Effects

The most commonly reported side effects of moxifloxacin include off label use, drug hypersensitivity, and dyspnoea, based on 38,594 FDA adverse event reports from 2004 to 2025. 5.7% of reports found the drug to be ineffective.

Moxifloxacin side effects

Percentages show how often each reaction appears relative to total reports for moxifloxacin.

1
Off Label Use6.9%2,659
2
Drug Hypersensitivity6.6%2,563
3
Dyspnoea6.5%2,499
4
Pain5.7%2,203
5
Drug Ineffective5.7%2,182
6
Pneumonia5.6%2,168
7
Asthma5.2%2,023
8
Vomiting5.1%1,971
9
Rash4.6%1,760
10
Fatigue4.4%1,682
11
Wheezing4.1%1,589
12
Nausea4.1%1,584
13
Neuropathy Peripheral4.0%1,543
14
Pyrexia3.7%1,441
15
Malaise3.7%1,420

These are voluntary reports and do not establish that moxifloxacin caused these reactions.

Report severity

77.7%Serious30,000 reports
30.9%Hospitalizations11,929 reports
10.1%Fatal3,882 reports

Seriousness is determined by the reporter, not by OpenClaim.

Moxifloxacin drug interactions

Other drugs that appear in adverse event reports alongside moxifloxacin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ciprofloxacin7.5%2,910
2
Prednisone7.2%2,797
3
Levofloxacin5.8%2,240
4
Rituximab5.7%2,207
5
Linezolid5.4%2,098
6
Fluticasone4.8%1,857
7
Pantoprazole-sodium4.4%1,680
8
Montelukast-sodium4.1%1,568
9
Acetaminophen3.6%1,395
10
Albuterol3.6%1,386
11
Adalimumab3.5%1,364
12
Salmeterol-xinafoate3.5%1,359
13
Etanercept3.1%1,179
14
Infliximab3.1%1,179
15
Hydromorphone-hydrochloride3.0%1,165

Taken alongside

1
Acetaminophen8.8%3,407
2
Prednisone7.9%3,048
3
Albuterol7.0%2,689
4
Aspirin6.6%2,556
5
Furosemide5.9%2,286
6
Fluticasone5.0%1,937
7
Levothyroxine-sodium5.0%1,931
8
Omeprazole4.9%1,872
9
Pantoprazole-sodium4.8%1,867
10
Ergocalciferol4.7%1,819
11
Prednisolone4.6%1,785
12
Azithromycin4.5%1,752
13
Dexamethasone4.4%1,701
14
Atorvastatin-calcium4.3%1,678
15
Amlodipine4.2%1,635

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports moxifloxacin side effects

52.6% of moxifloxacin adverse event reports involve female patients and 35.4% involve male patients. The largest age group is adult at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.6%
Male35.4%
Unknown11.9%

Age group

< 20.5%
2–111.0%
12–171.1%
18–6457.7%
65+39.8%

What is moxifloxacin used for

Conditions and purposes for which patients were taking moxifloxacin when the adverse event was reported.

Abdominal AbscessAbdominal InfectionAbdominal OperationAbdominal PainAbdominal Pain UpperAbdominal Wall AbscessAbscessAbscess IntestinalAbscess LimbAcanthamoeba InfectionAcanthamoeba KeratitisAccidental ExposureAcinetobacter InfectionAcinetobacter Test PositiveAcne

Showing 15 of 1,436 indications

Moxifloxacin brand names and reporting trend

Moxifloxacin is sold under the brand name Avelox In Sodium Chloride 0.8% In Plastic Container.

Brand names

Avelox In Sodium Chloride 0.8% In Plastic Container27

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking moxifloxacin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.