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Moxetumomab Side Effects

The most commonly reported side effects of moxetumomab include capillary leak syndrome, haemolytic uraemic syndrome, and death, based on 71 FDA adverse event reports from 2009 to 2025. 4.2% of reports found the drug to be ineffective.

Moxetumomab side effects

Percentages show how often each reaction appears relative to total reports for moxetumomab.

1
Capillary Leak Syndrome18.3%13
2
Haemolytic Uraemic Syndrome18.3%13
3
Death9.9%7
4
Weight Increased8.5%6
5
Pneumonia5.6%4
6
Hairy Cell Leukaemia5.6%4
7
Dyspnoea5.6%4
8
Drug Ineffective4.2%3
9
Fatigue4.2%3
10
Headache4.2%3
11
Hypoxia4.2%3
12
Blood Creatinine Increased4.2%3
13
Fluid Overload4.2%3
14
Renal Failure4.2%3
15
Septic Shock4.2%3

These are voluntary reports and do not establish that moxetumomab caused these reactions.

Report severity

74.6%Serious53 reports
31.0%Hospitalizations22 reports
22.5%Fatal16 reports

Seriousness is determined by the reporter, not by OpenClaim.

Moxetumomab drug interactions

Other drugs that appear in adverse event reports alongside moxetumomab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Rituximab15.5%11
2
Vemurafenib5.6%4
3
Cladribine5.6%4
4
Prednisone4.2%3
5
Vincristine-sulfate4.2%3
6
Pentostatin4.2%3
7
Methotrexate2.8%2
8
Mercaptopurine2.8%2
9
Filgrastim2.8%2
10
Bendamustine-hydrochloride2.8%2
11
Quetiapine-fumarate1.4%1
12
Voriconazole1.4%1
13
Blinatumomab1.4%1
14
Gabapentin1.4%1
15
Venlafaxine1.4%1

Taken alongside

1
Acyclovir7.0%5
2
Aspirin5.6%4
3
Simvastatin4.2%3
4
Allopurinol4.2%3
5
Glipizide4.2%3
6
Rituximab2.8%2
7
Vemurafenib2.8%2
8
Acetaminophen2.8%2
9
Tamsulosin-hydrochloride2.8%2
10
Famotidine2.8%2
11
Cladribine2.8%2
12
Bisoprolol-fumarate2.8%2
13
Metoprolol2.8%2
14
Omeprazole2.8%2
15
Cefepime-hydrochloride2.8%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports moxetumomab side effects

15.5% of moxetumomab adverse event reports involve female patients and 63.4% involve male patients. The largest age group is elderly at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female15.5%
Male63.4%
Unknown21.1%

Age group

< 20.0%
2–110.0%
12–172.9%
18–6431.4%
65+65.7%

What is moxetumomab used for

Conditions and purposes for which patients were taking moxetumomab when the adverse event was reported.

Acute Lymphocytic Leukaemia RecurrentAcute Lymphocytic Leukaemia RecurrentHairy Cell LeukaemiaHairy Cell Leukaemia RecurrentHairy Cell LeukaemiaProduct Used For Unknown IndicationProduct Used For Unknown Indication

Moxetumomab brand names and reporting trend

Moxetumomab is sold under the brand name Lumoxiti.

Brand names

Lumoxiti16

Quarterly reports (20092025)

2009202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking moxetumomab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.