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Monomethyl Side Effects

The most commonly reported side effects of monomethyl include flushing, pruritus, and product dose omission issue, based on 896 FDA adverse event reports from 2020 to 2025.

Monomethyl side effects

Percentages show how often each reaction appears relative to total reports for monomethyl.

1
Flushing38.5%345
2
Pruritus12.3%110
3
Product Dose Omission Issue9.3%83
4
Nausea8.3%74
5
Erythema7.3%65
6
Abdominal Discomfort7.0%63
7
Abdominal Pain Upper5.7%51
8
Fatigue5.2%47
9
Diarrhoea5.0%45
10
Rash4.9%44
11
Dizziness4.8%43
12
Paraesthesia4.7%42
13
Feeling Hot4.6%41
14
Headache4.4%39
15
Burning Sensation3.8%34

These are voluntary reports and do not establish that monomethyl caused these reactions.

Report severity

10.3%Serious92 reports
4.7%Hospitalizations42 reports
0.2%Fatal2 reports

Seriousness is determined by the reporter, not by OpenClaim.

Monomethyl drug interactions

Other drugs that appear in adverse event reports alongside monomethyl. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Teriflunomide0.8%7
2
Diroximel-fumarate0.7%6
3
Dalfampridine0.3%3
4
Aspirin0.2%2
5
Ponesimod0.2%2
6
Ublituximab-xiiy0.2%2
7
Ocrelizumab0.2%2
8
Cetirizine-hydrochloride0.1%1
9
Azelastine0.1%1
10
Estrogens0.1%1
11
Tolterodine-tartrate0.1%1
12
Pantoprazole-sodium0.1%1
13
Levothyroxine-sodium0.1%1
14
Venlafaxine0.1%1
15
Prednisone0.1%1

Taken alongside

1
Ergocalciferol5.5%49
2
Gabapentin3.8%34
3
Baclofen3.0%27
4
Aspirin2.2%20
5
Levothyroxine-sodium1.7%15
6
Ibuprofen1.6%14
7
Omeprazole1.5%13
8
Acetaminophen1.5%13
9
Atorvastatin-calcium1.5%13
10
Losartan-potassium1.5%13
11
Tizanidine-hydrochloride1.3%12
12
Amlodipine1.3%12
13
Bupropion1.3%12
14
Rosuvastatin1.2%11
15
Buspirone-hydrochloride1.2%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports monomethyl side effects

3.7% of monomethyl adverse event reports involve female patients and 0.7% involve male patients. The largest age group is adult at 79%. These figures reflect who reports side effects, not underlying risk.

Sex

Female3.7%
Male0.7%
Unknown95.6%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6479.2%
65+20.8%

What is monomethyl used for

Conditions and purposes for which patients were taking monomethyl when the adverse event was reported.

Facial PainMultiple SclerosisMultiple SclerosisMultiple Sclerosis RelapseNeuralgiaProduct Used For Unknown IndicationProduct Used For Unknown IndicationRelapsing Multiple SclerosisRelapsing-remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis

Monomethyl brand names and reporting trend

Monomethyl is sold under the brand name Bafiertam.

Brand names

Bafiertam4

Quarterly reports (20202025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking monomethyl with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.