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Momelotinib Side Effects

The most commonly reported side effects of momelotinib include thrombocytopenia, death, and anaemia, based on 1,169 FDA adverse event reports from 2010 to 2025. 7.4% of reports found the drug to be ineffective.

Momelotinib side effects

Percentages show how often each reaction appears relative to total reports for momelotinib.

1
Thrombocytopenia9.5%111
2
Death7.9%92
3
Drug Ineffective7.4%86
4
Anaemia6.7%78
5
Myelofibrosis5.7%67
6
Diarrhoea5.4%63
7
Fatigue5.0%58
8
Pneumonia4.8%56
9
Condition Aggravated4.7%55
10
Dizziness4.4%51
11
Haemoglobin Decreased4.2%49
12
Platelet Count Decreased4.0%47
13
Nausea3.7%43
14
Neuropathy Peripheral3.6%42
15
Splenomegaly3.4%40

These are voluntary reports and do not establish that momelotinib caused these reactions.

Report severity

70.0%Serious818 reports
23.4%Hospitalizations274 reports
16.3%Fatal190 reports

Seriousness is determined by the reporter, not by OpenClaim.

Momelotinib drug interactions

Other drugs that appear in adverse event reports alongside momelotinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ruxolitinib6.9%81
2
Pacritinib-citrate0.9%11
3
Furosemide0.5%6
4
Deferasirox0.4%5
5
Avapritinib0.4%5
6
Febuxostat0.4%5
7
Lamivudine0.4%5
8
Sildenafil-citrate0.4%5
9
Amoxicillin0.3%4
10
Cytarabine0.3%4
11
Luspatercept-aamt0.3%3
12
Fedratinib-hydrochloride0.3%3
13
Acyclovir0.3%3
14
Paclitaxel0.2%2
15
Gemcitabine0.2%2

Taken alongside

1
Ruxolitinib5.6%66
2
Hydroxyurea2.1%24
3
Aspirin2.0%23
4
Allopurinol1.9%22
5
Atorvastatin-calcium1.8%21
6
Furosemide1.7%20
7
Amlodipine1.6%19
8
Levothyroxine-sodium1.5%18
9
Prednisone1.3%15
10
Acetaminophen1.1%13
11
Pantoprazole-sodium1.0%12
12
Ergocalciferol1.0%12
13
Bisoprolol-fumarate1.0%12
14
Metformin0.9%11
15
Metoprolol0.9%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports momelotinib side effects

25.6% of momelotinib adverse event reports involve female patients and 25.1% involve male patients. The largest age group is elderly at 84%. These figures reflect who reports side effects, not underlying risk.

Sex

Female25.6%
Male25.1%
Unknown49.3%

Age group

< 20.3%
2–110.3%
12–170.0%
18–6415.0%
65+84.5%

What is momelotinib used for

Conditions and purposes for which patients were taking momelotinib when the adverse event was reported.

AmyloidosisAnaemiaAutoimmune AnaemiaBone PainCardiac FailureCentral Nervous System NeoplasmChronic DiseaseChronic Lymphocytic LeukaemiaChronic Myelomonocytic LeukaemiaColon CancerDry MouthEmbolismEssential ThrombocythaemiaHaematological MalignancyHaematological Neoplasm

Showing 15 of 51 indications

Momelotinib brand names and reporting trend

Momelotinib is sold under the brand name Ojjaara.

Brand names

Ojjaara747

Quarterly reports (20102025)

2010201620242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking momelotinib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.