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Minoxidil Side Effects

The most commonly reported side effects of minoxidil include adverse drug reaction, alopecia, and product use issue, based on 66,716 FDA adverse event reports from 2004 to 2025. 15.9% of reports found the drug to be ineffective.

Minoxidil side effects

Percentages show how often each reaction appears relative to total reports for minoxidil.

1
Drug Ineffective15.9%10,584
2
Adverse Drug Reaction12.8%8,540
3
Alopecia11.2%7,502
4
Product Use Issue8.0%5,328
5
Off Label Use7.7%5,134
6
Application Site Pruritus5.6%3,752
7
Product Use In Unapproved Indication3.9%2,609
8
Pruritus3.8%2,523
9
Intentional Product Misuse3.7%2,475
10
Overdose3.6%2,388
11
Hair Texture Abnormal3.5%2,351
12
Incorrect Dose Administered3.3%2,222
13
Inappropriate Schedule Of Drug Administration3.2%2,124
14
Wrong Technique In Product Usage Process3.0%2,018
15
Inappropriate Schedule Of Product Administration2.9%1,926

These are voluntary reports and do not establish that minoxidil caused these reactions.

Report severity

8.8%Serious5,885 reports
3.6%Hospitalizations2,373 reports
0.7%Fatal492 reports

Seriousness is determined by the reporter, not by OpenClaim.

Minoxidil drug interactions

Other drugs that appear in adverse event reports alongside minoxidil. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Finasteride0.7%459
2
Omeprazole0.5%336
3
Esomeprazole0.4%278
4
Pantoprazole-sodium0.4%246
5
Dupilumab0.3%188
6
Lansoprazole0.3%169
7
Amlodipine0.2%162
8
Sodium-oxybate0.2%132
9
Spironolactone0.2%121
10
Clonidine0.2%119
11
Dextrose0.2%116
12
Tacrolimus0.2%113
13
Patiromer-sorbitex-calcium0.2%107
14
Ketoconazole0.1%98
15
Furosemide0.1%95

Taken alongside

1
Ergocalciferol2.8%1,845
2
Levothyroxine-sodium2.4%1,631
3
Aspirin2.4%1,591
4
Amlodipine2.1%1,426
5
Biotin2.1%1,411
6
Metoprolol1.9%1,255
7
Atorvastatin-calcium1.9%1,236
8
Furosemide1.7%1,110
9
Lisinopril1.7%1,101
10
Calcium1.5%999
11
Clonidine1.4%959
12
Acetaminophen1.4%902
13
Losartan-potassium1.3%856
14
Omeprazole1.3%851
15
Simvastatin1.2%768

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports minoxidil side effects

42.6% of minoxidil adverse event reports involve female patients and 46.9% involve male patients. The largest age group is adult at 61%. These figures reflect who reports side effects, not underlying risk.

Sex

Female42.6%
Male46.9%
Unknown10.6%

Age group

< 20.5%
2–110.5%
12–170.7%
18–6461.3%
65+37.0%

What is minoxidil used for

Conditions and purposes for which patients were taking minoxidil when the adverse event was reported.

Abdominal PainAccidental ExposureAccidental Exposure To ProductAcneAdverse Drug ReactionAdverse EventAlcohol AbuseAlcohol UseAlopeciaAlopecia AreataAlopecia EffluviumAlopecia ScarringAlopecia TotalisAlopecia UniversalisAnaemia

Showing 15 of 240 indications

Minoxidil brand names and reporting trend

Minoxidil is sold under the brand name Minodyl.

Brand names

Minodyl34,203

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking minoxidil with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.