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Mezlocillin Side Effects

The most commonly reported side effects of mezlocillin include pruritus, rash, and stevens-johnson syndrome, based on 59 FDA adverse event reports from 2004 to 2025.

Mezlocillin side effects

Percentages show how often each reaction appears relative to total reports for mezlocillin.

1
Pruritus16.9%10
2
Rash15.3%9
3
Stevens-johnson Syndrome13.6%8
4
Toxic Epidermal Necrolysis13.6%8
5
Cardiac Arrest13.6%8
6
Blister13.6%8
7
Conjunctivitis13.6%8
8
Skin Lesion13.6%8
9
Circulatory Collapse13.6%8
10
Lip Erosion13.6%8
11
Skin Exfoliation13.6%8
12
Drug Exposure During Pregnancy5.1%3
13
Dyspnoea5.1%3
14
Pyrexia5.1%3
15
White Blood Cell Count Decreased5.1%3

These are voluntary reports and do not establish that mezlocillin caused these reactions.

Report severity

98.3%Serious58 reports
54.2%Hospitalizations32 reports
13.6%Fatal8 reports

Seriousness is determined by the reporter, not by OpenClaim.

Mezlocillin drug interactions

Other drugs that appear in adverse event reports alongside mezlocillin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ciprofloxacin15.3%9
2
Sodium-succinate13.6%8
3
Omeprazole13.6%8
4
Dimenhydrinate13.6%8
5
Spironolactone13.6%8
6
Pentazocine13.6%8
7
Loperamide-hydrochloride13.6%8
8
Heparin11.9%7
9
Dextrose11.9%7
10
Insulin10.2%6
11
Metronidazole10.2%6
12
Methylprednisolone8.5%5
13
Sodium-chloride6.8%4
14
Acetaminophen6.8%4
15
Ibuprofen6.8%4

Taken alongside

1
Sodium-chloride22.0%13
2
Potassium-chloride20.3%12
3
Magnesium-acetate-tetrahydrate8.5%5
4
Pantoprazole-sodium8.5%5
5
Prednisone8.5%5
6
Heparin6.8%4
7
Acetaminophen6.8%4
8
Aspirin6.8%4
9
Lansoprazole6.8%4
10
Nifedipine6.8%4
11
Promethazine-hydrochloride5.1%3
12
Sulfamethoxazole5.1%3
13
Furosemide5.1%3
14
Levofloxacin5.1%3
15
Atorvastatin-calcium5.1%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports mezlocillin side effects

57.6% of mezlocillin adverse event reports involve female patients and 30.5% involve male patients. The largest age group is adult at 43%. These figures reflect who reports side effects, not underlying risk.

Sex

Female57.6%
Male30.5%
Unknown11.9%

Age group

< 211.8%
2–117.8%
12–170.0%
18–6443.1%
65+37.3%

What is mezlocillin used for

Conditions and purposes for which patients were taking mezlocillin when the adverse event was reported.

Abdominal PainAntibiotic ProphylaxisAsthma-chronic Obstructive Pulmonary Disease Overlap SyndromeAnti-infective TherapyAntibiotic TherapyBacteraemiaBronchitisBronchitisCholangitisCholangitisEvidence Based TreatmentInfectionInfection ProphylaxisInfection ProphylaxisLung Infection

Showing 15 of 26 indications

Mezlocillin brand names and reporting trend

Mezlocillin is sold under the brand name Mezlin.

Brand names

Mezlin63

Quarterly reports (20042025)

20042025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking mezlocillin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.