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Methscopolamine Side Effects

The most commonly reported side effects of methscopolamine include nausea, diarrhoea, and fatigue, based on 451 FDA adverse event reports from 2004 to 2025. 5.3% of reports found the drug to be ineffective.

Methscopolamine side effects

Percentages show how often each reaction appears relative to total reports for methscopolamine.

1
Nausea8.0%36
2
Diarrhoea6.9%31
3
Fatigue5.5%25
4
Drug Ineffective5.3%24
5
Vomiting5.3%24
6
Pain4.4%20
7
Headache4.4%20
8
Off Label Use4.2%19
9
Drug Interaction4.0%18
10
Anxiety3.5%16
11
Nausea3.3%15
12
Abdominal Pain3.3%15
13
Weight Decreased3.3%15
14
Dyspnoea3.3%15
15
Dizziness3.1%14

These are voluntary reports and do not establish that methscopolamine caused these reactions.

Report severity

70.7%Serious319 reports
38.1%Hospitalizations172 reports
9.3%Fatal42 reports

Seriousness is determined by the reporter, not by OpenClaim.

Methscopolamine drug interactions

Other drugs that appear in adverse event reports alongside methscopolamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab5.3%24
2
Sodium-oxybate5.1%23
3
Ethinyl-estradiol3.8%17
4
Drospirenone3.5%16
5
Esomeprazole2.9%13
6
Aspirin2.4%11
7
Omeprazole2.2%10
8
Spironolactone2.0%9
9
Quetiapine-fumarate1.8%8
10
Bosentan1.8%8
11
Ambrisentan1.8%8
12
Citalopram-hydrobromide1.8%8
13
Infliximab1.6%7
14
Ruxolitinib1.6%7
15
Phenylephrine1.6%7

Taken alongside

1
Acetaminophen22.2%100
2
Furosemide16.6%75
3
Omeprazole14.9%67
4
Levothyroxine-sodium14.2%64
5
Ondansetron13.7%62
6
Prednisone13.1%59
7
Ergocalciferol13.1%59
8
Aspirin12.9%58
9
Albuterol12.0%54
10
Gabapentin10.2%46
11
Spironolactone10.0%45
12
Fluticasone9.8%44
13
Pantoprazole-sodium9.5%43
14
Hydrocodone9.3%42
15
Tramadol-hydrochloride9.3%42

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports methscopolamine side effects

63.4% of methscopolamine adverse event reports involve female patients and 31.9% involve male patients. The largest age group is adult at 62%. These figures reflect who reports side effects, not underlying risk.

Sex

Female63.4%
Male31.9%
Unknown4.7%

Age group

< 20.3%
2–111.7%
12–174.0%
18–6462.0%
65+32.0%

What is methscopolamine used for

Conditions and purposes for which patients were taking methscopolamine when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAntiallergic TherapyAbdominal PainAbdominal Pain UpperBipolar DisorderCardiac FailureCardiac Failure ChronicColitisColitis UlcerativeCrohn^s DiseaseCardiac AmyloidosisCardiac FailureCardiac Failure Chronic

Showing 15 of 57 indications

Methscopolamine brand names and reporting trend

Methscopolamine is sold under the brand name Methscopolamine Bromide.

Brand names

Methscopolamine Bromide211

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking methscopolamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.