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Methdilazine Side Effects

The most commonly reported side effects of methdilazine include hepatotoxicity, condition aggravated, and intervertebral disc disorder, based on 7 FDA adverse event reports from 2005 to 2021. 42.9% of reports found the drug to be ineffective.

Methdilazine side effects

Percentages show how often each reaction appears relative to total reports for methdilazine.

1
Drug Ineffective42.9%3
2
Hepatotoxicity28.6%2
3
Condition Aggravated14.3%1
4
Intervertebral Disc Disorder14.3%1
5
Kyphosis14.3%1
6
Vertigo Positional14.3%1
7
Anxiety14.3%1
8
Drug Ineffective14.3%1
9
Weight Increased14.3%1
10
Oedema14.3%1
11
Skin Lesion14.3%1
12
Erythema14.3%1
13
Drug Eruption14.3%1
14
Macule14.3%1
15
Pruritus14.3%1

These are voluntary reports and do not establish that methdilazine caused these reactions.

Report severity

85.7%Serious6 reports
28.6%Hospitalizations2 reports
0.0%Fatal0 reports

Seriousness is determined by the reporter, not by OpenClaim.

Methdilazine drug interactions

Other drugs that appear in adverse event reports alongside methdilazine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab42.9%3
2
Tofacitinib42.9%3
3
Atorvastatin-calcium14.3%1
4
Paroxetine14.3%1
5
Levocetirizine-dihydrochloride14.3%1
6
Cetirizine-hydrochloride14.3%1
7
Aspirin14.3%1
8
Quetiapine-fumarate14.3%1
9
Acetaminophen14.3%1

Taken alongside

1
Denosumab42.9%3
2
Diclofenac42.9%3
3
Metformin42.9%3
4
Sitagliptin42.9%3
5
Sarilumab42.9%3
6
Ergocalciferol28.6%2
7
Prednisolone28.6%2
8
Pantoprazole-sodium28.6%2
9
Anastrozole28.6%2
10
Aspirin14.3%1
11
Isosorbide14.3%1
12
Magnesium-acetate-tetrahydrate14.3%1
13
Omeprazole14.3%1
14
Loratadine14.3%1
15
Pseudoephedrine14.3%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports methdilazine side effects

71.4% of methdilazine adverse event reports involve female patients and 14.3% involve male patients. The largest age group is elderly at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female71.4%
Male14.3%
Unknown14.3%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6433.3%
65+66.7%

What is methdilazine used for

Conditions and purposes for which patients were taking methdilazine when the adverse event was reported.

Product Used For Unknown IndicationPain

Methdilazine brand names and reporting trend

Methdilazine is sold under the brand name Tacaryl.

Brand names

Tacaryl6

Quarterly reports (20052021)

20052021

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking methdilazine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.