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Methazolamide Side Effects

The most commonly reported side effects of methazolamide include fatigue, dizziness, and headache, based on 382 FDA adverse event reports from 2004 to 2025. 9.7% of reports found the drug to be ineffective.

Methazolamide side effects

Percentages show how often each reaction appears relative to total reports for methazolamide.

1
Fatigue9.9%38
2
Drug Ineffective9.7%37
3
Dizziness7.3%28
4
Headache7.1%27
5
Dyspnoea6.8%26
6
Asthenia6.0%23
7
Blood Pressure Increased5.8%22
8
Off Label Use5.5%21
9
Pain In Extremity5.5%21
10
Anxiety5.2%20
11
Death5.2%20
12
Arthralgia5.2%20
13
Pain5.0%19
14
Nasopharyngitis5.0%19
15
Fall4.7%18

These are voluntary reports and do not establish that methazolamide caused these reactions.

Report severity

64.9%Serious248 reports
28.5%Hospitalizations109 reports
8.4%Fatal32 reports

Seriousness is determined by the reporter, not by OpenClaim.

Methazolamide drug interactions

Other drugs that appear in adverse event reports alongside methazolamide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide6.8%26
2
Brimonidine-tartrate6.0%23
3
Acetazolamide5.0%19
4
Timolol5.0%19
5
Cenegermin-bkbj5.0%19
6
Ergocalciferol4.7%18
7
Topiramate4.2%16
8
Dexamethasone3.9%15
9
Octreotide-acetate3.7%14
10
Dorzolamide-hydrochloride3.1%12
11
Latanoprost3.1%12
12
Calcium-carbonate2.9%11
13
Tacrolimus2.6%10
14
Aspirin2.6%10
15
Alendronate-sodium2.6%10

Taken alongside

1
Timolol20.7%79
2
Brimonidine-tartrate18.3%70
3
Aspirin17.5%67
4
Levothyroxine-sodium17.0%65
5
Ergocalciferol15.2%58
6
Atorvastatin-calcium12.8%49
7
Furosemide11.5%44
8
Dorzolamide-hydrochloride11.3%43
9
Latanoprost11.3%43
10
Omeprazole10.5%40
11
Acetaminophen10.2%39
12
Lisinopril10.2%39
13
Insulin9.2%35
14
Amlodipine9.2%35
15
Prednisone9.2%35

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports methazolamide side effects

56.8% of methazolamide adverse event reports involve female patients and 38.2% involve male patients. The largest age group is elderly at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female56.8%
Male38.2%
Unknown5.0%

Age group

< 20.0%
2–110.4%
12–170.7%
18–6442.9%
65+56.0%

What is methazolamide used for

Conditions and purposes for which patients were taking methazolamide when the adverse event was reported.

ArthritisAutoimmune RetinopathyAbdominal DiscomfortBenign Intracranial HypertensionCrohn's DiseaseCystoid Macular OedemaCondition AggravatedDiabetic Retinal OedemaDiffuse Large B-cell LymphomaDrug Use For Unknown IndicationDizzinessEssential TremorEye PainEar DiscomfortEar Pain

Showing 15 of 50 indications

Methazolamide brand names and reporting trend

Methazolamide is sold under the brand name Methazolamide.

Brand names

Methazolamide359

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking methazolamide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.